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Image Unavailable-BOSSBS-5660R-A647

Anti-RELA Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Varenummer: (BOSSBS-5660R-A647)
Leverandør: Bioss
Beskrivelse: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5376R-A350

Anti-G3BP1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Varenummer: (BOSSBS-5376R-A350)
Leverandør: Bioss
Beskrivelse: May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5376R-HRP

Anti-G3BP1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Varenummer: (BOSSBS-5376R-HRP)
Leverandør: Bioss
Beskrivelse: May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5376R-FITC

Anti-G3BP1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-5376R-FITC)
Leverandør: Bioss
Beskrivelse: May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1253R-CY3

Anti-AQP3 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-1253R-CY3)
Leverandør: Bioss
Beskrivelse: Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
UOM: 1 * 100 µl
Image Unavailable-ENZOADICSA600F

Anti-CLIP Mouse Monoclonal Antibody

Varenummer: (ENZOADICSA600F)
Leverandør: ENZO LIFE SCIENCES
Beskrivelse: CLIP (class II-associated invariant chain peptide) is an important peptide in the MHC-II antigen processing pathway, formed by the enzymatic cleavage of amino acids 81-104 from the invariant chain. During MHC-II synthesis in the ER and transport to endocytic vesicles, the antigen binding site of MHC-II is obstructed by the presence of the invariant chain. As the MHC-II complex moves through the Golgi, the invariant chain is degraded, leaving the CLIP fragment in the MHC-II peptide binding groove. CLIP is eventually displaced by the loading of antigenic peptides, followed by presentation on the APC cell surface to CD4+ T-cells.
UOM: 1 * 1 Each
Image Unavailable-BOSSBS-1253R-A488

Anti-AQP3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Varenummer: (BOSSBS-1253R-A488)
Leverandør: Bioss
Beskrivelse: Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1253R-HRP

Anti-AQP3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Varenummer: (BOSSBS-1253R-HRP)
Leverandør: Bioss
Beskrivelse: Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1253R-A555

Anti-AQP3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Varenummer: (BOSSBS-1253R-A555)
Leverandør: Bioss
Beskrivelse: Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11861R-CY7

Anti-KALRN Rabbit Polyclonal Antibody (Cy7®)

Varenummer: (BOSSBS-11861R-CY7)
Leverandør: Bioss
Beskrivelse: HAP1 (huntingtin-associated protein 1) binds to huntingtin (1). Huntingtin is a protein that contains a polyglutamine region and when the number of glutamine repeats exceeds 35, the gene encodes a version of huntingtin that leads to Huntington’s disease (HD) (2,3). The ability of HAP1 to bind to huntingtin is enhanced by an expanded polyglutamine repeat region (1). HAP1 shows neuronal localization and moves with huntingtin in nerve fibers (4,5). HAP1 is primarily expressed in brain tissue, with greater expression in the olfactory bulb and brain stem (1). Mouse HAP1 is localized to membrane-bound organelles including large endosomes, tubulovesicular structures and budding vesicles in neurons (6). Duo, also designated huntingtin-associated protein interacting protein or HAPIP, binds Huntingtin-associated protein 1 (HAP1) and may have a role in vesicle trafficking and cytoskeletal function.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13338R-CY5

Anti-GFM1 Rabbit Polyclonal Antibody (Cy5®)

Varenummer: (BOSSBS-13338R-CY5)
Leverandør: Bioss
Beskrivelse: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5514R-CY5.5

Anti-NFKBIA Rabbit Polyclonal Antibody (Cy5.5®)

Varenummer: (BOSSBS-5514R-CY5.5)
Leverandør: Bioss
Beskrivelse: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3309R-A555

Anti-NPM Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Varenummer: (BOSSBS-3309R-A555)
Leverandør: Bioss
Beskrivelse: This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3309R-A350

Anti-NPM Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Varenummer: (BOSSBS-3309R-A350)
Leverandør: Bioss
Beskrivelse: This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5514R-A750

Anti-NFKBIA Tyr42 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Varenummer: (BOSSBS-5514R-A750)
Leverandør: Bioss
Beskrivelse: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3309R-CY5

Anti-NPM Rabbit Polyclonal Antibody (Cy5®)

Varenummer: (BOSSBS-3309R-CY5)
Leverandør: Bioss
Beskrivelse: This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009].
UOM: 1 * 100 µl
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