Du Søgte efter: ENZO LIFE SCIENCES

Varenummer: (ENZOADIMSA225E)

Leverandør: ENZO LIFE SCIENCES

Beskrivelse: GAD, glutamic acid decarboxylase, is an integral membrane protein that catalyzes the formation of gamma-aminobutyric acid (GABA), which is an inhibitory neurotransmitter. The biological functions of GAD and GABA extend beyond regulation of neurotransmission to include effects on the immune system and modulation of cell proliferation, protein synthesis, and metabolism.

UOM: 1 * 1 Each

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Varenummer: (ENZOADIMSA110F)

Leverandør: ENZO LIFE SCIENCES

Beskrivelse: The Myc-Tag (EQKLISEEDL) corresponds to the partial peptide sequence of the human c-myc gene product. Recognizes the Myc-tag of Myc-tagged recombinant proteins.

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Leverandør: ENZO LIFE SCIENCES

Beskrivelse: The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

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Leverandør: ENZO LIFE SCIENCES

Beskrivelse: Anti-HSPA8 Mouse Monoclonal Antibody [clone: N27F3-4]

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Leverandør: ENZO LIFE SCIENCES

Beskrivelse: Calcineurin is a Ca2+/Calmodulin-dependent serine/threonine protein phosphatase. The active enzyme is a heterodimer consisting of a catalytic A subunit and a myristylated regulatory B subunit that binds calcium. Calcineurin, which is the target of immunosuppressant drugs such as cyclosporin A and FK506, controls the translocation of Nuclear factors of activated T-cells (NFAT), a family of transcriptional activators that control the expression of cytokine genes essential to immune response, from the cytosol into the nucleus of activated T-cells.

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Leverandør: ENZO LIFE SCIENCES

Beskrivelse: Hsp20 is a member of the family of small heat shock proteins (sHsps), with homology to Hsp25, Hsp27, and alphaB-crystallin.

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Varenummer: (ENZOBMLSA4680100)

Leverandør: ENZO LIFE SCIENCES

Beskrivelse: Host: Mouse, Isotype: IgG1

UOM: 1 * 1 Each

New Product Tilbud

Varenummer: (ENZOBMLSA4930015)

Leverandør: ENZO LIFE SCIENCES

Beskrivelse: Host: Mouse

UOM: 1 * 1 Each

New Product Tilbud

Varenummer: (ENZOBMLSA4770100)

Leverandør: ENZO LIFE SCIENCES

Beskrivelse: Host: Rabbit

UOM: 1 * 100 µl

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Varenummer: (ENZOBMLLG60300100)

Leverandør: ENZO LIFE SCIENCES

Beskrivelse: Host: Mouse, Isotype: IgG1

UOM: 1 * 100 µl

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Leverandør: ENZO LIFE SCIENCES

Beskrivelse: Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; "free" iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5'- or 3'- UTRs of the mRNAs. To date, three identified heme oxygenase isoforms are part of the HO system that catalyze heme into biliverdin and carbon monoxide. These are inducible HO-1 or Hsp32, constitutive HO-2 that is abundant in the brain and testis, and HO-3 which is related to HO-2 but is the product of a different gene. The HO system is the rate-limiting step in heme degradation and HO activity decreases the levels of heme which is a well known potent catalyst of lipid peroxidation and oxygen radical formation.

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Varenummer: (ENZOADISAB2200500)

Leverandør: ENZO LIFE SCIENCES

Beskrivelse: Immunoglobulin G (IgG) is an immunoglobulin monomer consisting of two (gamma) heavy chains and two light chains.  Each IgG molecule contains two antigen binding domains and a single effector (Fc) domain.

UOM: 1 * 0,5 mL

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Varenummer: (ENZOENZC34930)

Leverandør: ENZO LIFE SCIENCES

Beskrivelse: Host: Mouse, Isotype: IgG1

UOM: 1 * 0,5 mL

New Product Tilbud

Varenummer: (ENZOENZC34904)

Leverandør: ENZO LIFE SCIENCES

Beskrivelse: Host: Mouse, Isotype: IgG1

UOM: 1 * 0,5 mL

New Product Tilbud

Varenummer: (ENZOALX804447C100)

Leverandør: ENZO LIFE SCIENCES

Beskrivelse: Host: Rat, Isotype: IgG1

UOM: 1 * 1 Each

New Product Tilbud

Varenummer: (ENZOALX804376RC100)

Leverandør: ENZO LIFE SCIENCES

Beskrivelse: The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. Ten human homologs of TLRs (TLR1-10) have been described. TLR8 gene contains three exons, two of which have coding function. TLR8 cDNA codes for a protein of approximate molecular weight of 120kDa.

UOM: 1 * 1 Each

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