Du Søgte efter: Tonbo Biosciences

Varenummer: (72-8076-M001)

Leverandør: Tonbo Biosciences

Beskrivelse: Rabbit anti-Mouse IgG (H&L) - Affinity Pure, HRP Conjugate

UOM: 1 * 1 mg

Tilbud

Varenummer: (72-8111-M001)

Leverandør: Tonbo Biosciences

Beskrivelse: Goat anti-Guinea Pig IgG (H&L) - Affinity Pure, HRP Conjugate

UOM: 1 * 1 mg

Tilbud

Varenummer: (72-8100-M001)

Leverandør: Tonbo Biosciences

Beskrivelse: Goat anti-Human IgG (H&L) - Affinity Pure, HRP Conjugate

UOM: 1 * 1 mg

Tilbud

Varenummer: (72-8093-M001)

Leverandør: Tonbo Biosciences

Beskrivelse: Goat anti-Mouse IgG Fc - Affinity Pure, HRP Conjugate, min x w/bovine, horse or human serum proteins

UOM: 1 * 1 mg

Tilbud

Varenummer: (72-8096-U500)

Leverandør: Tonbo Biosciences

Beskrivelse: Goat anti-mouse IgG (H&L), F(ab')2 fragment, HRP conjugate, min x w/bovine, horse, human, pig or rabbit serum protein

UOM: 1 * 0,5 mg

Tilbud

Varenummer: (70-8015-M001)

Leverandør: Tonbo Biosciences

Beskrivelse: Goat anti-Human IgA (alpha chain), F(ab')2 Fragment - Affinity Pure

UOM: 1 * 1 mg

Tilbud

Varenummer: (80-4724-U100)

Leverandør: Tonbo Biosciences

Beskrivelse: The C1.18.4 immunoglobulin is useful as an isotype-matched control. The C.1.18.4 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2a antibodies.

UOM: 1 * 1 Each

Tilbud

Leverandør: Tonbo Biosciences

Beskrivelse: The MY31 antibody reacts with human CD56, also known as the neural cell adhesion molecule (NCAM), a glycoprotein which is a member of the immunoglobulin superfamily. The 140 kDa isoform of CD56 is expressed on human NK cells and NK-T cells, with increased expression levels on activated NK lymphocytes. The CD56 antigen is also expressed by neurons and is reported to play a role in nervous system development and neural cell-to-cell adhesion.

Varenummer: (40-0112-U100)

Leverandør: Tonbo Biosciences

Beskrivelse: The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165 to 170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

UOM: 1 * 1 Each

Tilbud

Leverandør: Tonbo Biosciences

Beskrivelse: The SK7 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Leverandør: Tonbo Biosciences

Beskrivelse: The EBVCS-5 antibody is specific for human CD23, also known as the low affinity IgE receptor (FceRII), a 45 kDa type II transmembrane protein and member of the immunoglobulin superfamily. It is expressed on most B cells and is upregulated upon activation. It is also present on mantle zone B cells, eosinophils, monocytes and a subset of T cells and platelets. CD23 plays a role in B cell development and differentiation, and also functions to regulate IgE production. Soluble secreted forms of CD23 have been reported to bind IgE, stimulate release of pro-inflammatory cytokines from monocytes, and play a role in B cell differentiation.

Varenummer: (70-4321-U100)

Leverandør: Tonbo Biosciences

Beskrivelse: Purified Rat IgG2a Isotype Control (2A3)

UOM: 1 * 1 Each

Tilbud

Leverandør: Tonbo Biosciences

Beskrivelse: The JES5-2A5 antibody is specific for mouse IL-10. IL-10 has numerous biological activities including the ability to inhibit both the synthesis of Th1 cytokines and proliferation of T cells. In the mouse, IL-10 is produced by phagocytic cells, conventional dendritic, cells, T cells, B cells, and NK cells. The JES5-2A5 antibody is a neutralizing antibody.

Leverandør: Tonbo Biosciences

Beskrivelse: The SK7 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Leverandør: Tonbo Biosciences

Beskrivelse: The UCHT2 antibody is specific for human CD5, a 67 kD transmembrane glycoprotein, that is expressed on most thymocytes, mature T cells, and a subset of B cells. CD5 is involved in modulating antigen receptor signaling in both T and B cells and binds to CD72, expressed on B cells.

Leverandør: Tonbo Biosciences

Beskrivelse: The OKT8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.