Du Søgte efter: ProSci Inc.

Varenummer: (PRSI6543P)

Leverandør: ProSci Inc.

Beskrivelse: RASSF6 peptide is used for blocking the activity of RASSF6 antibody.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI45-028)

Leverandør: ProSci Inc.

Beskrivelse: Anti-CBL Goat Polyclonal Antibody

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI96-056)

Leverandør: ProSci Inc.

Beskrivelse: Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI27-882)

Leverandør: ProSci Inc.

Beskrivelse: APOBEC3G is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI27-869)

Leverandør: ProSci Inc.

Beskrivelse: UBP1 is an important SF1-independent transcriptional activator stimulating P450scc expression in human placental JEG-3 cells, whereas LBP-9 modulates the action of UBP1, exerting both positive and negative effects

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI90-169)

Leverandør: ProSci Inc.

Beskrivelse: Contactin-6 is a member of the contactins, which mediate cell surface interactions during nervous system development. Contactin-6 has a key role in the formation of glutamatergic, but not GABAergic, synapses during postnatal development of the hippocampal formation as well as the cerebellum. It is involved in oligodendrocytes generation by acting as a ligand of Notch1. It is also involved in motor coordination.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI6991P)

Leverandør: ProSci Inc.

Beskrivelse: CASKIN1 peptide is used for blocking the activity of CASKIN1 antibody.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI96-627)

Leverandør: ProSci Inc.

Beskrivelse: Polymeric immunoglobulin receptor (PIGR) is also known as Poly-Ig receptor, which can be cleaved into membrane secretory component (SC). PIGR is a type I transmembrane glycoprotein or a member of the immunoglobulin superfamily, and is synthesized by secretory epithelial cells and delivered to the basolateral plasma membrane where it can bind larger polymers of IgA (pIgA ) and pentameric IgM. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI7009P)

Leverandør: ProSci Inc.

Beskrivelse: EED peptide is used for blocking the activity of EED antibody.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI91-921)

Leverandør: ProSci Inc.

Beskrivelse: N-acetylgalactosaminyltransferase 7(GALNT7) is expressed in uterus, retina, kidney, small intestine, omentum, stomach and CNS.It belongs to the glycosyltransferase 2 family and galNAc-T subfamily. The enzyme encoded by this gene controls the initiation step of mucin-type O-linked protein glycosylation and transfer of N-acetylgalactosamine to serine and threonine amino acid residues. This enzyme is a type II transmembrane protein and shares common sequence motifs with other family members. This protein may function as a follow-up enzyme in the initiation step of O-glycosylation.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI92-273)

Leverandør: ProSci Inc.

Beskrivelse: Annexin A3（ANXA3）contains 4 annexin repeats and belongs to the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. ANXA3 is Inhibitor of phospholipase A2 and cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. it also also play a role in anti-coagulant properties.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI96-681)

Leverandør: ProSci Inc.

Beskrivelse: Serpin A1 is also known as Alpha-1-antitrypsin (A1AT), serum trypsin inhibitor, alpha-1 proteinase inhibitor (A1PI), AAT, which belongs to the serpin family. Most serpins inactivate enzymes by binding to them covalently, requiring very high levels to perform their function. Like all serine protease inhibitors, A1AT has a characteristic secondary structure of beta sheets and alpha helices. Serpin A1 / A1AT is inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form of SerpinA1 inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Serpin A1 / A1AT protects tissues from enzymes of inflammatory cells, especially neutrophil elastase. Defects in SERPINA1 are the cause of alpha-1-antitrypsin deficiency (A1ATD).

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI91-417)

Leverandør: ProSci Inc.

Beskrivelse: Human Fractalkine (CX3CL1) is a member of the CX3C family of chemokines. Human Fractalkine contains both chemokine and mucin domain. The soluble form of Fractalkine is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane bound form of Fractalkine promotes leukocytes adhesion to endothelial cells. Fractalkine regulates leukocyte adhesion and migration processes at the endothelium and binds to CX3CR1. Natural Human Fractalkine is produced as a long protein (373-amino acid). The mucin-like stalk permits it to bind to the cell surface.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI91-279)

Leverandør: ProSci Inc.

Beskrivelse: Protein NDRG1 is a member of the N-Myc Downregulated Gene family, which is part of the alpha/ beta Hydrolase superfamily. Protein NDRG1 is a cytoplasmic protein that is involved in stress responses, hormone responses, cell growth and differentiation. Protein NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Protein NDRG1 mutuations are reported to be the cause for hereditary motor and sensory neuropathy-Lom. Decreased NDRG1 expression in glioma is linked to tumor progression; overexpression of NDRG1 is connected to malignant status of esophageal cancer.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI6495P)

Leverandør: ProSci Inc.

Beskrivelse: RILPL1 peptide is used for blocking the activity of RILPL1 antibody.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI2147P)

Leverandør: ProSci Inc.

Beskrivelse: DRAK1 peptide is used for blocking the activity of DRAK1 antibody.

UOM: 1 * 1 Each

Tilbud