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Varenummer: (ABCAAB218439-100)
Leverandør: Abcam
Beskrivelse: Mouse monoclonal [rOV-TL12/30] to Cytokeratin 7.
UOM: 1 * 1 Each


Varenummer: (ABCAAB19298-50)
Leverandør: Abcam
Beskrivelse: Mouse monoclonal [13C9] to UL42.
UOM: 1 * 1 Each


Varenummer: (PRSI91-943)
Leverandør: ProSci Inc.
Beskrivelse: Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon- gamma (IFN- gamma ) or type II interferon that plays an important role in activating the macrophages or other cells.
UOM: 1 * 1 Each


Varenummer: (ABNOPAB18297)
Leverandør: Abnova
Beskrivelse: Rabbit polyclonal antibody raised against synthetic peptide of IL18.
UOM: 1 * 1 Each


Varenummer: (ORIGTA324665)
Leverandør: OriGene
Beskrivelse: Anti-ULK2 Rabbit Polyclonal Antibody
UOM: 1 * 400 µl


Varenummer: (PRSI13-933)
Leverandør: ProSci Inc.
Beskrivelse: Anti-IL18 Rabbit Polyclonal Antibody
UOM: 1 * 50 µl


Varenummer: (PRSI90-506)
Leverandør: ProSci Inc.
Beskrivelse: Interleukin-18 (IL-18) is a costimulatory factor for production of interferon-gamma (IFN-gamma) in response to toxic shock and shares functional similarities with IL-12. IL-18 is synthesised as a precursor 24kDa molecule without a signal peptide and must be cleaved to produce an active molecule. IL-1 converting enzyme (ICE; Caspase-1) cleaves pro-IL-18 at aspartic acid in the P1 position, producing the mature, bioactive peptide that is readily released from the cells. It is reported that IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IFN-gamma is produced by activated T or NK cells and plays critical roles in the defense against microbiral pathogens. IFN-gamma activates macrophages and enhances NK activity and B cell maturation, proliferation and Ig secretion. IFN-gamma also induces expression of MHC class I and II antigens and inhibits osteoclast activation. IL-18 acts on T helper type-1 (Th1) T cells and in combination with IL-12 strongly induces them to produce IFN-gamma. Pleiotropic effects of IL-18 have also been reported, such as enhancement production of IFN-gamma and GM-CSF in peripheral blood mononuclear cells, production of Th1 cytokines, IL-2, GM-CSF, IFN-gamma in T cells and enhancement of Fas ligand expression by Th1 cells.
UOM: 1 * 1 Each


Varenummer: (PRSI45-766)
Leverandør: ProSci Inc.
Beskrivelse: Anti-l12b Goat Polyclonal Antibody
UOM: 1 * 1 Each


Varenummer: (ABNORAB01840.100UL)
Leverandør: Abnova
Beskrivelse: Anti-USP28 Rabbit Recombinant Antibody [clone: R08-7I7]
UOM: 1 * 100 µl


Varenummer: (ABNOP8781.25UG)
Leverandør: Abnova
Beskrivelse: Recombinant Human IL18 (from E. coli)
UOM: 1 * 1 Each


Varenummer: (ABNOPAB16177)
Leverandør: Abnova
Beskrivelse: Rabbit polyclonal antibody raised against IL18.
UOM: 1 * 1 Each


Varenummer: (PRSI92-503)
Leverandør: ProSci Inc.
Beskrivelse: Interleukin-18 (IL18, also known as interferon-gamma inducing factor) is a protein which in mouse is encoded by the IL18 gene, belongs to the IL-1 family. Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells
UOM: 1 * 1 Each


Varenummer: (ABNOPAB19122)
Leverandør: Abnova
Beskrivelse: Rabbit polyclonal antibody raised against full length recombinant IL18.
UOM: 1 * 1 Each


Varenummer: (ANTIA83377-100)
Leverandør: ANTIBODIES.COM
Beskrivelse: Goat polyclonal antibody to IL18 for ELISA and WB with samples derived from human.
UOM: 1 * 1 Each

New Product


Varenummer: (ABNOP7327.10UG)
Leverandør: Abnova
Beskrivelse: Recombinant Rat IL18 (from E. coli)
UOM: 1 * 1 Each


Varenummer: (PRSI90-507)
Leverandør: ProSci Inc.
Beskrivelse: Interleukin-18 (IL-18) is a costimulatory factor for production of interferon-gamma (IFN-gamma) in response to toxic shock and shares functional similarities with IL-12. IL-18 is synthesised as a precursor 24kDa molecule without a signal peptide and must be cleaved to produce an active molecule. IL-1 converting enzyme (ICE; Caspase-1) cleaves pro-IL-18 at aspartic acid in the P1 position, producing the mature, bioactive peptide that is readily released from the cells. It is reported that IL-18 is produced from Kupffer cells, activated macrophages, keratinocytes, intestinal epithelial cells, osteoblasts, adrenal cortex cells and murine diencephalon. IFN-gamma is produced by activated T or NK cells and plays critical roles in the defense against microbiral pathogens. IFN-gamma activates macrophages and enhances NK activity and B cell maturation, proliferation and Ig secretion. IFN-gamma also induces expression of MHC class I and II antigens and inhibits osteoclast activation. IL-18 acts on T helper type-1 (Th1) T cells and in combination with IL-12 strongly induces them to produce IFN-gamma. Pleiotropic effects of IL-18 have also been reported, such as enhancement production of IFN-gamma and GM-CSF in peripheral blood mononuclear cells, production of Th1 cytokines, IL-2, GM-CSF, IFN-gamma in T cells and enhancement of Fas ligand expression by Th1 cells.
UOM: 1 * 1 Each


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Dette produkt er mærket som begrænset og kan kun købes af godkendte Shipping konti. Hvis du har brug for yderligere hjælp, e-mail VWR Regulatory Department på Regulatory_Affairs@vwr.com
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