Du Søgte efter: ul128

Varenummer: (BOSSBS-5820R-A488)

Leverandør: Bioss

Beskrivelse: Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability. Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN. Also involved in G2 DNA damage checkpoint, by deubiquitinating CLSPN, and preventing its degradation by the anaphase promoting complex/cyclosome (APC/C). In contrast, it does not deubiquitinate PLK1. Specifically deubiquitinates MYC in the nucleoplasm, leading to prevent MYC degradation by the proteasome: acts by specifically interacting with isoform 1 of FBXW7 (FBW7alpha) in the nucleoplasm and counteracting ubiquitination of MYC by the SCF(FBW7) complex. In contrast, it does not interact with isoform 4 of FBXW7 (FBW7gamma) in the nucleolus, allowing MYC degradation and explaining the selective MYC degradation in the nucleolus.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-5820R-FITC)

Leverandør: Bioss

Beskrivelse: Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability. Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN. Also involved in G2 DNA damage checkpoint, by deubiquitinating CLSPN, and preventing its degradation by the anaphase promoting complex/cyclosome (APC/C). In contrast, it does not deubiquitinate PLK1. Specifically deubiquitinates MYC in the nucleoplasm, leading to prevent MYC degradation by the proteasome: acts by specifically interacting with isoform 1 of FBXW7 (FBW7alpha) in the nucleoplasm and counteracting ubiquitination of MYC by the SCF(FBW7) complex. In contrast, it does not interact with isoform 4 of FBXW7 (FBW7gamma) in the nucleolus, allowing MYC degradation and explaining the selective MYC degradation in the nucleolus.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-0896R)

Leverandør: Bioss

Beskrivelse: Human cytomegalovirus (HCMV) is a ubiquitous herpes virus that leads to a life-long persistence. The frequency of infection ranges from 50% to 100% in the general adult population. Human cytomegalovirus causes severe and often fatal disease in immunocompromised individuals including recipients of organ transplants and AIDS patients. It routinely reactivates in healthy virus carriers, but this is usually controlled by the host immune response. Monocytes may be an important reservoir for latent HCMV; however, the primary reservoir may be a more primitive cell from the myeloid lineage. Reactivation may result from cellular differentiation or inflammation.

UOM: 1 * 100 µl

Tilbud

Varenummer: (ABCAAB207323-100)

Leverandør: Abcam

Beskrivelse: Rabbit monoclonal [EPR19956] to IL-18.

UOM: 1 * 100 µl

MSDS Tilbud

Varenummer: (ABNOPAB7305)

Leverandør: Abnova

Beskrivelse: Goat polyclonal antibody raised against synthetic peptide of IL12B.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BSBTA00918-1)

Leverandør: Boster Bio

Beskrivelse: Rabbit IgG polyclonal antibody for IL12A detection. Tested with WB, IHC-P, Direct ELISA in Human;Mouse;Rat.

UOM: 1 * 1 Each

Tilbud

Varenummer: (ORIGTA328496)

Leverandør: OriGene

Beskrivelse: Anti-Il12a Goat Polyclonal Antibody

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI92-363)

Leverandør: ProSci Inc.

Beskrivelse: IL-12 is involved in the differentiation of naive T cells into Th1 cells. It is known as a T cell-stimulating factor, which can stimulate the growth and function of T cells. It stimulates the production of interferon-gamma (IFN- gamma ) and tumour necrosis factor-alpha (TNF- alpha) from T cells and natural killer (NK) cells, and reduces IL-4 mediated suppression of IFN- gamma . T cells that produce IL-12 have a coreceptor, CD30, which is associated with IL-12 activity.IL-12 plays an important role in the activities of natural killer cells and T lymphocytes. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes.

UOM: 1 * 1 Each

Tilbud

Varenummer: (USBIU1500-72)

Leverandør: US Biological

Beskrivelse: Anti-ULK2 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Tilbud

Varenummer: (USBI043601)

Leverandør: US Biological

Beskrivelse: Anti-ULK2 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Tilbud

Varenummer: (USBIU1500-72A)

Leverandør: US Biological

Beskrivelse: Anti-ULK2 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Tilbud

Varenummer: (USBIR2031-29)

Leverandør: US Biological

Beskrivelse: Anti-S6 Ribosomal Protein Rabbit Monoclonal Antibody [clone: 5i128]

UOM: 1 * 100 µl

Tilbud

Leverandør: Abcam

Beskrivelse: Rabbit monoclonal [EPR12279] to hnRNP U/p120 - BSA and Azide free.

Varenummer: (ABCAAB308335-100)

Leverandør: Abcam

Beskrivelse: Rabbit monoclonal [HL1028] to Androgen Receptor - BSA and Azide free.

UOM: 1 * 100 µl

Tilbud

Varenummer: (ABCAAB308356-100)

Leverandør: Abcam

Beskrivelse: Rabbit monoclonal [HL1287] to ASFV p54 - BSA and Azide free.

UOM: 1 * 100 µl

Tilbud

Varenummer: (PRSI92-630)

Leverandør: ProSci Inc.

Beskrivelse: Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulphide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

UOM: 1 * 1 Each

Tilbud