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Varenummer: (BOSSBS-2390R)
Leverandør: Bioss
Beskrivelse: ACO2, also referred to as aconitate hydratase, citrate hydrolyase or aconitase, is an iron-sulfur hydrolyase that catalyzes the non-limiting interconversion of citrate and isocitrate in the tricarboxylic acid cycle. It is expressed in the mitochondria and maintains a citrate:isocitrate ratio of approximately 10:1. ACO2 contains a redox-sensitive iron-sulfur cluster that exists in two states: active (Fe4S4) and inactive (Fe3S4). ACO2 activity is dependent on the state of this cluster as well as the presence of two conserved cysteine residues. In normal prostate epithelial cells ACO2 activity is prevented due to the high levels of zinc inhibiting the enzyme. In these citrate-producing epithelial cells citrate oxidation is impaired allowing citrate to accumulate and exhibit a citrate:isocitrate ratio of approximately 30:1. In malignant prostate cells zinc is unable to accumulate, therefore ACO2 activity resumes and citrate is oxidized.
UOM: 1 * 100 µl


Varenummer: (PRSI56-286)
Leverandør: ProSci Inc.
Beskrivelse: RBL2 is a key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. RBL2 may act as a tumor suppressor.
UOM: 1 * 400 µl

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Leverandør: Abcam
Beskrivelse: Anti-Aconitase 2 Rabbit Monoclonal Antibody [clone: EPR8283(B)]

Varenummer: (USBIA0660-01D)
Leverandør: US Biological
Beskrivelse: Anti-ACO1 Goat Polyclonal Antibody
UOM: 1 * 1 Each


Varenummer: (PRSI27-083)
Leverandør: ProSci Inc.
Beskrivelse: ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM: 1 * 1 Each


Leverandør: Abcam
Beskrivelse: Anti-Aconitase 2 Rabbit Monoclonal Antibody [clone: EPR8282(B)]

Varenummer: (ABCAAB129069-10)
Leverandør: Abcam
Beskrivelse: Anti-ACO2 Rabbit Monoclonal Antibody [clone: EPR8282]
UOM: 1 * 10 µl


Varenummer: (BSBTPB9973)
Leverandør: Boster Bio
Beskrivelse: Aconitase 2, mitochondrial is a protein that in humans is encoded by the ACO2 gene. The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification.
UOM: 1 * 1 Each


Leverandør: Abcam
Beskrivelse: Anti-Aconitase 1/ACO1 Rabbit Monoclonal Antibody [clone: EPR7226(2)]

Leverandør: Merck
Beskrivelse: Trimethyl orthoacetat, Sigma-Aldrich®
Varenummer: (646679-5G)
Leverandør: SIGMA ALDRICH MICROSCOPY
Beskrivelse: 1,1,2-Trimethyl-3-(4-sulfobutyl)benz[e]indolium, inner salt, Dye content 90 % (1,1,2-Trimethyl-3-(4-sulfobutyl)-1H-benz[e]indolium hydroxide, inner salt; 1-(4-Sulfobutyl)-2,3,3-trimethyl-4,5-benzindolium, inner salt)
UOM: 1 * 5 g


Varenummer: (262134R)
Leverandør: VWR Chemicals
Beskrivelse: (±)-3,5,5-Trimethyl-1-hexanol, TECHNICAL
UOM: 1 * 500 mL

Leverandør: Thermo Fisher Scientific
Beskrivelse: Trimethyl thiophosphate
Leverandør: Apollo Scientific
Beskrivelse: Trimethyl orthobutyrate

Leverandør: Thermo Fisher Scientific
Beskrivelse: Trimethyl orthoacetat 98+%
Leverandør: TCI
Beskrivelse: Trimethyl orthobutyrate ≥96.0% (by GC)

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