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Image Unavailable-BOSSBS-6588R-A350

Anti-ADAMTS10 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Varenummer: (BOSSBS-6588R-A350)
Leverandør: Bioss
Beskrivelse: ADAMTS10 is a member of the ADAMs family of proteinases with Thrombospondin motifs. The catalytic site of ADAMTS10 is typical of the metalloproteinase catalytic domains, with an HExxHxxxxxH sequence, perhaps giving these enzymes some shared specificity. ADAMTS10 is closest in homology to ADAMTS6, sharing 53% overall identity. Functional mutations in ADAMTS10 have been linked to Weill Marchesani syndrome, a connective tissue disorder marked by fibrillin 1 misprocessing. ADAMTS10 has also been reported to be over expressed in breast cancer tissues and cell lines.
UOM: 1 * 100 µl
Product Image-612-5060

Målekolber, Klasse B, SILBERBRAND

Leverandør: Brand
Beskrivelse: Borosilicate glass 3.3, med prop i PP.

Image Unavailable-BOSSBS-2400R-CY5

Anti-MDC1 Rabbit Polyclonal Antibody (Cy5®)

Varenummer: (BOSSBS-2400R-CY5)
Leverandør: Bioss
Beskrivelse: Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2400R-A750

Anti-MDC1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Varenummer: (BOSSBS-2400R-A750)
Leverandør: Bioss
Beskrivelse: Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilisation of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7692R-CY3

Anti-RLN1 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-7692R-CY3)
Leverandør: Bioss
Beskrivelse: Relaxin is a peptide hormone produced by the corpora lutea of ovaries during pregnancy in many mammalian species, including man. The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, relaxin may influence the timing of parturition. Like insulin, relaxin consists of two peptide chains, A and B, covalently linked by disulfide bonds. By further analogy to insulin, the two peptides are synthesized as a single-chain precursor polypeptide with the B chain at the NH2-terminus.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8017R

Anti-CLN6 Rabbit Polyclonal Antibody

Varenummer: (BOSSBS-8017R)
Leverandør: Bioss
Beskrivelse: CLN6, a 311 amino acid protein, has seven predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness; part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8017R-A680

Anti-CLN6 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Varenummer: (BOSSBS-8017R-A680)
Leverandør: Bioss
Beskrivelse: CLN6, a 311 amino acid protein, has seven predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localises to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness; part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7692R-A750

Anti-Relaxin 1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Varenummer: (BOSSBS-7692R-A750)
Leverandør: Bioss
Beskrivelse: Relaxin is a peptide hormone produced by the corpora lutea of ovaries during pregnancy in many mammalian species, including man. The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, relaxin may influence the timing of parturition. Like insulin, relaxin consists of two peptide chains, A and B, covalently linked by disulfide bonds. By further analogy to insulin, the two peptides are synthesised as a single-chain precursor polypeptide with the B chain at the NH2-terminus.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7692R-A680

Anti-Relaxin 1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Varenummer: (BOSSBS-7692R-A680)
Leverandør: Bioss
Beskrivelse: Relaxin is a peptide hormone produced by the corpora lutea of ovaries during pregnancy in many mammalian species, including man. The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, relaxin may influence the timing of parturition. Like insulin, relaxin consists of two peptide chains, A and B, covalently linked by disulfide bonds. By further analogy to insulin, the two peptides are synthesised as a single-chain precursor polypeptide with the B chain at the NH2-terminus.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7692R-HRP

Anti-RLN1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Varenummer: (BOSSBS-7692R-HRP)
Leverandør: Bioss
Beskrivelse: Relaxin is a peptide hormone produced by the corpora lutea of ovaries during pregnancy in many mammalian species, including man. The secretion of the hormone into the blood stream just before parturition results in a marked softening and lengthening of the pubic symphysis and a softening of the cervix, which facilitates the birth process. By inhibiting uterine contractions, relaxin may influence the timing of parturition. Like insulin, relaxin consists of two peptide chains, A and B, covalently linked by disulfide bonds. By further analogy to insulin, the two peptides are synthesized as a single-chain precursor polypeptide with the B chain at the NH2-terminus.
UOM: 1 * 100 µl
Product Image-BRND2.37266

Volumetric flasks, class A, blue graduation, BLAUBRAND®

Leverandør: Brand
Beskrivelse: Borosilicate glass 3.3, with glass stopper.

Image Unavailable-BOSSBS-15581R

Anti-IkB beta Ser19 Rabbit Polyclonal Antibody

Varenummer: (BOSSBS-15581R)
Leverandør: Bioss
Beskrivelse: The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3562R

Anti-RELB Rabbit Polyclonal Antibody

Varenummer: (BOSSBS-3562R)
Leverandør: Bioss
Beskrivelse: The NFKB complex consists of NFKB1 or NFKB2 bound to REL, RELA, or RELB. The NFKB complex is inhibited by I kappa B proteins (NFKBIA, or NFKBIB), which inactivate NF kappa B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I kappa B proteins by kinases (IKBKA, or IKBKB,) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B complex. For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6588R-A555

Anti-ADAMTS10 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Varenummer: (BOSSBS-6588R-A555)
Leverandør: Bioss
Beskrivelse: ADAMTS10 is a member of the ADAMs family of proteinases with Thrombospondin motifs. The catalytic site of ADAMTS10 is typical of the metalloproteinase catalytic domains, with an HExxHxxxxxH sequence, perhaps giving these enzymes some shared specificity. ADAMTS10 is closest in homology to ADAMTS6, sharing 53% overall identity. Functional mutations in ADAMTS10 have been linked to Weill Marchesani syndrome, a connective tissue disorder marked by fibrillin 1 misprocessing. ADAMTS10 has also been reported to be over expressed in breast cancer tissues and cell lines.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2400R-A488

Anti-MDC1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Varenummer: (BOSSBS-2400R-A488)
Leverandør: Bioss
Beskrivelse: Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1.
UOM: 1 * 100 µl
Product Image-612-5062

Målekolber, Klasse A, BLAUBRAND® ETERNA

Leverandør: Brand
Beskrivelse: Borosilikatglas 3.3, med prop i PP.

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