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Image Unavailable-BOSSBS-8874R-A350

Anti-GPBAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Varenummer: (BOSSBS-8874R-A350)
Leverandør: Bioss
Beskrivelse: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8874R-FITC

Anti-GPBAR1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-8874R-FITC)
Leverandør: Bioss
Beskrivelse: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8874R-CY7

Anti-GPBAR1 Rabbit Polyclonal Antibody (Cy7®)

Varenummer: (BOSSBS-8874R-CY7)
Leverandør: Bioss
Beskrivelse: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8874R-CY5

Anti-GPBAR1 Rabbit Polyclonal Antibody (Cy5®)

Varenummer: (BOSSBS-8874R-CY5)
Leverandør: Bioss
Beskrivelse: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8874R-CY3

Anti-GPBAR1 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-8874R-CY3)
Leverandør: Bioss
Beskrivelse: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8874R-A647

Anti-GPBAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Varenummer: (BOSSBS-8874R-A647)
Leverandør: Bioss
Beskrivelse: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8874R-A555

Anti-GPBAR1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Varenummer: (BOSSBS-8874R-A555)
Leverandør: Bioss
Beskrivelse: The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart, skeletal muscle, spleen, kidney, liver, small intestine, placenta, and leukocytes, but not in brain, colon (without mucosa), thymus, or lung. TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis. Bile acids activate mitogen-activated protein (MAP) kinase pathways, specifically induce TGR5 internalization, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, and cause rapid intracellular cAMP production. Bile acids also provoke TGR5 to suppress macrophage functions. TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, such as obesity, type II diabetes, hyperlipidemia, and atherosclerosis.
UOM: 1 * 100 µl
Image Unavailable-APOSBID6721-100MG

2'-Deoxyguanosine-5'-triphosphate trisodium salt (dGTP-Na3)

Leverandør: Apollo Scientific
Beskrivelse: 2'-Deoxyguanosine-5'-triphosphate trisodium salt (dGTP-Na3)

Image Unavailable-40026.

5-Bromouridine-5′-triphosphate sodium salt (BrUTP ) 10 mM in TE buffer

Varenummer: (40026.)
Leverandør: Biotium
Beskrivelse: BrUTP (5-Bromouridine-5′-triphosphate) can be enzymatically incorporated into RNA and detected with anti-BrdU antibodies.
UOM: 1 * 25 µl
Image Unavailable-40033.

Biotin-11-uridine-5'-triphosphate, tetralithium salt (Biotin-11-UTP) 10 mM in buffer (Tris-HCl, pH 7.5)

Varenummer: (40033.)
Leverandør: Biotium
Beskrivelse: Biotin-11-UTP (biotin-11-uridine-5'-triphosphate, tetralithium salt) can be enzymatically incorporated into RNA. The number 11 is the number of atoms in the linker between biotin and UTP.
UOM: 1 * 25 µl
Image Unavailable-ICNA0210190705

Guanosine 97.0-103.0%, off-white powder

Leverandør: MP Biomedicals
Beskrivelse: Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. Guanosine can be phosphorylated to become guanosine monophosphate (GMP), cyclic guanosine monophosphate (cGMP), guanosine diphosphate (GDP), and guanosine triphosphate (GTP). These forms play important roles in various biochemical processes such as synthesis of nucleic acids and proteins, photosynthesis, muscle contraction and intracellular signal transduction (cGMP). When guanine is attached by its N9 nitrogen to the C1 carbon of adeoxyribose ring it is known as deoxyguanosine.
Guanosine is required for an RNA splicing reaction in mRNA, when a "self-splicing" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein. The antiviral drug aciclovir, often used in herpes treatment, is structurally similar to guanosine.

Product Image-USBI035096

Anti-ENTPD5 Rabbit Polyclonal Antibody

Varenummer: (USBI035096)
Leverandør: US Biological
Beskrivelse: Anti-ENTPD5 Rabbit Polyclonal Antibody
UOM: 1 * 200 µl
Image Unavailable-1.24518.0005

Bathocuproin sulphonate disodium salt analyse reagens, Supelco®

Varenummer: (1.24518.0005)
Leverandør: Merck
Beskrivelse: Bathocuproin sulphonate disodium salt analytical reagent, Supelco®
UOM: 1 * 5 g

MSDS


Image Unavailable-40036.

Biotin-11-2′-deoxycytidine-5′-triphosphate, tetralithium salt (Biotin-11-dCTP) 1 mM in TE buffer (pH 7.5)

Varenummer: (40036.)
Leverandør: Biotium
Beskrivelse: Biotin-11-dCTP (Biotin-11-2′-deoxycytidine-5′-triphosphate, tetralithium salt) can be enzymatically incorporated into DNA via nick translation, random priming, or 3′-end terminal labeling. The number 11 is the number of atoms in the linker between biotin and dCTP.
UOM: 1 * 50 µl
Image Unavailable-11890-1G

Bathophenanthrolinedisulphonic acid disodium salt trihydrate, Supelco®

Leverandør: Merck
Beskrivelse: Bathophenanthrolinedisulphonic acid disodium salt trihydrate, Supelco®

Image Unavailable-N5000-500MG

Naphthol AS-MX phosphate disodium salt, Sigma-Aldrich®

Leverandør: SIGMA ALDRICH MICROSCOPY
Beskrivelse: Naphthol AS-MX phosphate disodium salt,phosphatase substrate

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