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Image Unavailable-BOSSBS-11034R-FITC

Anti-MYBPC1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11034R-FITC)
Leverandør: Bioss
Beskrivelse: MYBPC1 is a 1,141 amino acid protein that contains three fibronectin type-III domains and seven Ig-like C2-type domains. Existing as a member of the immunoglobulin superfamily, MYBPC1 functions as a thick filament-associated protein that localizes to striated muscle bands in vertebrae and is thought to modify the activity of select ATPases. Additionally, MYBPC1 may play a role in the modulation of muscle contraction and in the overall structural integrity of the cell. The gene encoding MYBPC1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and Trisomy 12p, which causes facial developmental defects and seizure disorders.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6584R-A680

Anti-DUT Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Varenummer: (BOSSBS-6584R-A680)
Leverandør: Bioss
Beskrivelse: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1721R-HRP

Anti-DUT Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Varenummer: (BOSSBS-1721R-HRP)
Leverandør: Bioss
Beskrivelse: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8270R-FITC

Anti-GIMAP4 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-8270R-FITC)
Leverandør: Bioss
Beskrivelse: Exhibits intrisinic GTPase activity. Shows a higher affinity for GDP over GTP (about 12-fold higher), and binding shows an absolute requirement for magnesium.Tissue specificity:Highly expressed in spleen and peripheral blood leukocytes that contain mostly T- and B-lymphocytes. Expressed specifically in resting T- and B-lymphocytes and expression significantly decreases during B- or T-lymphocyte activation. Expressed at lower levels in thymus, ovary, colon and small intestine.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11945R-FITC

Anti-RITA1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11945R-FITC)
Leverandør: Bioss
Beskrivelse: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf52 gene product has been provisionally designated C12orf52 pending further characterization.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11003R-FITC

Anti-ESYT2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11003R-FITC)
Leverandør: Bioss
Beskrivelse: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The FAM62A gene product has been provisionally designated FAM62A pending further characterization.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11997R-FITC

Anti-DDAH1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11997R-FITC)
Leverandør: Bioss
Beskrivelse: DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production (1,2). Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation (3). DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues (1).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6089R-FITC

Anti-RASSF8 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-6089R-FITC)
Leverandør: Bioss
Beskrivelse: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6987R-FITC

Anti-TMEM263 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-6987R-FITC)
Leverandør: Bioss
Beskrivelse: C12orf23 (chromosome 12 open reading frame 23), also known as FLJ11721, FLJ13959 or MGC17943, is a 116 amino acid multi-pass membrane protein belonging to the UPF0444 family. C12orf23 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a number of skeletal deformities, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.
UOM: 1 * 100 µl
Product Image-AATB17093

5-Propargylamino-3'-azidomethyl-dUTP

Varenummer: (AATB17093)
Leverandør: AAT BIOQUEST
Beskrivelse: 5-Propargylamino-3'-azidomethyl-dUTP is a key building block for preparing fluorescent conjugates that are used in the next generation sequencing (NGS).
UOM: 1 * 1 Each
Product Image-AATB17009

TF4-dUTP 1 mM in TRIS buffer (pH 7.5)

Varenummer: (AATB17009)
Leverandør: AAT BIOQUEST
Beskrivelse: The dye-modified deoxyuridine 5'-triphosphates (such as aminoallyl-dUTP) can be used to produce dye-containing DNA by conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.
UOM: 1 * 1 Each
Product Image-AATB17010

TF5-dUTP 1 mM in TRIS buffer (pH 7.5)

Varenummer: (AATB17010)
Leverandør: AAT BIOQUEST
Beskrivelse: The dye-modified deoxyuridine 5'-triphosphates (such as aminoallyl-dUTP) can be used to produce dye-containing DNA by conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.
UOM: 1 * 1 Each
Image Unavailable-BOSSBS-13667R-FITC

Anti-STAP2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-13667R-FITC)
Leverandør: Bioss
Beskrivelse: Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues (1,2). Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states (1,2). STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK (3). BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines (4). Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain (5). STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis (3).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11324R-FITC

Anti-NOVA1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11324R-FITC)
Leverandør: Bioss
Beskrivelse: Nova-1 and Nova-2 are members of a superfamily of protein regulators of RNA metabolism in neurons. Both are nuclear RNA binding proteins with K homology motifs, conserved protein sequences which bind to RNA (1,2). Nova proteins, normally sequestered in the central nervous system, are expressed by systemic tumors in patients with the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia (POMA) (3,4). Nova-1 is expressed in the hindbrain and ventral spinal cord and Nova-2 is expressed in the neocortex and hippocampus (4). Nova-1 is necessary for regulating neuron-specific alternative splicing of the glycine receptor Alpha2 pre-mRNA (5).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11406R-FITC

Anti-ZNF461 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11406R-FITC)
Leverandør: Bioss
Beskrivelse: GIOT-1 is a 563 amino acid protein belonging to the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localized to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9743R-FITC

Anti-ANKLE2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-9743R-FITC)
Leverandør: Bioss
Beskrivelse: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKLE2 (ankyrin repeat and LEM domain containing 2), also known as LEMD7, is a 938 amino acid single-pass membrane protein containing an ANK repeat and a LEM domain. Exsiting as two isoforms produced by alternative splicing events, the gene encoding ANKLE2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
UOM: 1 * 100 µl
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