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Product Image-AATB17010

TF5-dUTP 1 mM in TRIS buffer (pH 7.5)

Varenummer: (AATB17010)
Leverandør: AAT BIOQUEST
Beskrivelse: The dye-modified deoxyuridine 5'-triphosphates (such as aminoallyl-dUTP) can be used to produce dye-containing DNA by conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.
UOM: 1 * 1 Each
Product Image-AATB17006

TF1-dUTP 1 mM in TRIS buffer (pH 7.5)

Varenummer: (AATB17006)
Leverandør: AAT BIOQUEST
Beskrivelse: The dye-modified deoxyuridine 5'-triphosphates (such as aminoallyl-dUTP) can be used to produce dye-containing DNA by conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.
UOM: 1 * 1 Each
Image Unavailable-BOSSBS-6089R-FITC

Anti-RASSF8 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-6089R-FITC)
Leverandør: Bioss
Beskrivelse: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11945R-FITC

Anti-RITA1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11945R-FITC)
Leverandør: Bioss
Beskrivelse: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf52 gene product has been provisionally designated C12orf52 pending further characterization.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11003R-FITC

Anti-ESYT2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11003R-FITC)
Leverandør: Bioss
Beskrivelse: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The FAM62A gene product has been provisionally designated FAM62A pending further characterization.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11997R-FITC

Anti-DDAH1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11997R-FITC)
Leverandør: Bioss
Beskrivelse: DDAH, a dimethylarginine dimethylaminohydrolase, hydrolyzes dimethyl arginine (ADMA) and monomethyl arginine (MMA), both inhibitors of nitric oxide synthases, and may be involved in in-vivo modulation of nitric oxide production (1,2). Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation (3). DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA) (4). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues (1).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6987R-FITC

Anti-TMEM263 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-6987R-FITC)
Leverandør: Bioss
Beskrivelse: C12orf23 (chromosome 12 open reading frame 23), also known as FLJ11721, FLJ13959 or MGC17943, is a 116 amino acid multi-pass membrane protein belonging to the UPF0444 family. C12orf23 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a number of skeletal deformities, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13667R-FITC

Anti-STAP2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-13667R-FITC)
Leverandør: Bioss
Beskrivelse: Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues (1,2). Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states (1,2). STAP-2 is a protein that contains a pleckstrin homology (PH) domain and an SH2 domain, and associates with BRK (3). BRK (breast tumor kinase, Sik) is a 451 amino acid, nonreceptor protein-tyrosine kinase that is overexpressed in breast tumors and metastatic melanoma cell lines (4). Similar to the Src family of intracellular kinses, BRK is comprised of an SH3 domain, an SH2 domain, and a catalytic domain (5). STAP-2 is susceptiple to tyrosine phosphorylation and may be invovled in tyrosine kinase-mediated signaling cascades, whose aberrant function may lead to metastis (3).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11406R-FITC

Anti-ZNF461 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11406R-FITC)
Leverandør: Bioss
Beskrivelse: GIOT-1 is a 563 amino acid protein belonging to the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localized to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events.
UOM: 1 * 100 µl
Product Image-AATB17041

iFluor® 488 PEG12-dUTP *1 mM in TE Buffer (pH 7,5)*

Varenummer: (AATB17041)
Leverandør: AAT BIOQUEST
Beskrivelse: This iFluor® 488-PEG12-dUTP conjugate has the same spectral properties to ChromaTide™ Alexa Fluor 488-dUTP.
UOM: 1 * 1 Each

New Product


Image Unavailable-BOSSBS-9743R-FITC

Anti-ANKLE2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-9743R-FITC)
Leverandør: Bioss
Beskrivelse: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKLE2 (ankyrin repeat and LEM domain containing 2), also known as LEMD7, is a 938 amino acid single-pass membrane protein containing an ANK repeat and a LEM domain. Exsiting as two isoforms produced by alternative splicing events, the gene encoding ANKLE2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-15130R-FITC

Anti-C21orf88 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-15130R-FITC)
Leverandør: Bioss
Beskrivelse: The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf88 gene product has been provisionally designated C21orf88 pending further characterization.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12919R-FITC

Anti-CK8 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-12919R-FITC)
Leverandør: Bioss
Beskrivelse: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11698R-FITC

Anti-HYPE/HIP13 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11698R-FITC)
Leverandør: Bioss
Beskrivelse: Huntingtin yeast partner E is a 458 amino acid single-pass membrane protein. HYPE is thought to interact with Huntingtin, a protein which induces neurodegeneration when mutated. HYPE also contains two tetratricopeptide repeats (TPR), which may be involved in protein-protein interaction. The gene that encodes HYPE is located on chromosome 12, which encodes over 1,100 genes within 132 million bases and makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.
UOM: 1 * 100 µl
Product Image-AATB17011

Violet 450-dUTP 1 mM in TRIS buffer, mFluor™ (pH 7.5)

Varenummer: (AATB17011)
Leverandør: AAT BIOQUEST
Beskrivelse: The dye-modified deoxyuridine 5'-triphosphates (such as aminoallyl-dUTP) can be used to produce dye-containing DNA by conventional enzymatic incorporation methods such as reverse transcription, nick translation, random primed labeling, or PCR.
UOM: 1 * 1 Each
Image Unavailable-BOSSBS-11324R-FITC

Anti-NOVA1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11324R-FITC)
Leverandør: Bioss
Beskrivelse: Nova-1 and Nova-2 are members of a superfamily of protein regulators of RNA metabolism in neurons. Both are nuclear RNA binding proteins with K homology motifs, conserved protein sequences which bind to RNA (1,2). Nova proteins, normally sequestered in the central nervous system, are expressed by systemic tumors in patients with the autoimmune disorder paraneoplastic opsoclonus-myoclonus ataxia (POMA) (3,4). Nova-1 is expressed in the hindbrain and ventral spinal cord and Nova-2 is expressed in the neocortex and hippocampus (4). Nova-1 is necessary for regulating neuron-specific alternative splicing of the glycine receptor Alpha2 pre-mRNA (5).
UOM: 1 * 100 µl
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