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Leverandør: MP Biomedicals
Beskrivelse: Lead tetraacetate smoothly induces the addition of difluorodiiodomethane to alkenes and alkynes.

Varenummer: (BOSSBS-0076R-A680)
Leverandør: Bioss
Beskrivelse: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalisation of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. In vitro, can reduce Cu(2+) and Fe(3+) to Cu(+) and Fe(2+), respectively. Beta-amyloid 42 is a more effective reductant than beta-amyloid 40. Beta-amyloid peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalysed oxidation of lipoproteins. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses.
UOM: 1 * 100 µl


Leverandør: Honeywell Chemicals
Beskrivelse: Titan(IV)oxid 99-100.5%, Puriss., meets analytical specification of BP, Ph. Eur., USP, Fluka™
Varenummer: (BOSSBS-0076R-A750)
Leverandør: Bioss
Beskrivelse: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity (By similarity). Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal death directly or is potentiated through Cu(2+)-mediated low-density lipoprotein oxidation. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I and IV. The splice isoforms that contain the BPTI domain possess protease inhibitor activity. Induces a AGER-dependent pathway that involves activation of p38 MAPK, resulting in internalisation of amyloid-beta peptide and leading to mitochondrial dysfunction in cultured cortical neurons. Provides Cu(2+) ions for GPC1 which are required for release of nitric oxide (NO) and subsequent degradation of the heparan sulfate chains on GPC1. Beta-amyloid peptides are lipophilic metal chelators with metal-reducing activity. Bind transient metals such as copper, zinc and iron. In vitro, can reduce Cu(2+) and Fe(3+) to Cu(+) and Fe(2+), respectively. Beta-amyloid 42 is a more effective reductant than beta-amyloid 40. Beta-amyloid peptides bind to lipoproteins and apolipoproteins E and J in the CSF and to HDL particles in plasma, inhibiting metal-catalysed oxidation of lipoproteins. Beta-APP42 may activate mononuclear phagocytes in the brain and elicit inflammatory responses.
UOM: 1 * 100 µl


Leverandør: Spectrum Chemical
Beskrivelse: Titanium Dioxide, USP is used as a food coloring. All Spectrum Chemical USP products are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.

Leverandør: Honeywell Chemicals
Beskrivelse: Mangan(IV)oxid ≥90% (RT), Technical Grade, aktiveret, Fluka™
Leverandør: MERCK PRODUCTION CHEMICALS
Beskrivelse: Titan(IV)oxid 99.0-100.5% (dried basis), EMPROVE® ESSENTIAL Ph. Eur., BP, USP, JP, E171, SAFC®
Varenummer: (BSENR-1381-100)
Leverandør: Biosensis
Beskrivelse: Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14. PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels. MMP2 isoform 2 mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways. Catalytic activity of MMP2 causes cleavage of gelatin type I and collagen types IV, V, VII, X. Cleaves the collagen-like sequence Pro-Gln-Gly-|-Ile-Ala-Gly-Gln. (Ref: uniprot.org).
UOM: 1 * 1 Each


Varenummer: (ICNA0202827)
Leverandør: MP Biomedicals
Beskrivelse: Siliciumdioxid, Ecochrom™ 32-63 µm
UOM: 1 * 2,5 kg


Varenummer: (ICNA0202071)
Leverandør: MP Biomedicals
Beskrivelse: Mean Pore Size: 60Å
Particle Size: 32-63 µm
UOM: 1 * 25 kg


Leverandør: Honeywell Chemicals
Beskrivelse: Siliciumdioxid, Purum p.a. 40-200 mesh, Fluka™
Varenummer: (ICNA0202826)
Leverandør: MP Biomedicals
Beskrivelse: Siliciumdioxid, Ecochrom™ 32-63 µm
UOM: 1 * 25 kg


Leverandør: Thermo Fisher Scientific
Beskrivelse: Vanadylsulfat pentahydrat 17-23% (v/v)
Leverandør: Honeywell Chemicals
Beskrivelse: Siliciumdioxid for cleaning of platinum crucibles, calcinated, crude, Fluka™
Leverandør: Roth Carl
Beskrivelse: Kvarts

Leverandør: Roth Carl
Beskrivelse: Kvarts

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