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Image Unavailable-BOSSBS-3001R-CY3

Anti-ACIN1 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-3001R-CY3)
Leverandør: Bioss
Beskrivelse: Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets; ACIN1 confers RNA-binding to the complex. The ASAP complex can inhibit RNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function. Induces apoptotic chromatin condensation after activation by CASP3. Regulates cyclin A1, but not cyclin A2, expression in leukemia cells.
UOM: 1 * 100 µl
Product Image-437117K

VWR®, Phosphate Buffered Saline (PBS), Low Phosphate, 10X

Varenummer: (437117K)
Leverandør: VWR Chemicals
Beskrivelse: Strålebehandlet PBS-koncentrat, egnet til skylning af celler efter fortynding.
UOM: 1 * 10 L

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Product Image-312-1171

Prøvetager, MiniSampler

Leverandør: BURKLE
Beskrivelse: The sample liquid only comes into contact with the suction hose and the original sample bottle. Cross-contamination is greatly reduced. Immediately after taking the sample, the bottles are sealed.
● PE MiniSampler for general sampling
● PTFE MiniSampler for ultra-pure sampling

Image Unavailable-BOSSBS-11250R-CY7

Anti-CD86 Rabbit Polyclonal Antibody (Cy7®)

Varenummer: (BOSSBS-11250R-CY7)
Leverandør: Bioss
Beskrivelse: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7725R-A680

Anti-SA2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Varenummer: (BOSSBS-7725R-A680)
Leverandør: Bioss
Beskrivelse: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7725R-A350

Anti-SA2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Varenummer: (BOSSBS-7725R-A350)
Leverandør: Bioss
Beskrivelse: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2738R-CY5.5

Anti-FANCD2 Rabbit Polyclonal Antibody (Cy5.5®)

Varenummer: (BOSSBS-2738R-CY5.5)
Leverandør: Bioss
Beskrivelse: Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation.DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4298R-CY5

Anti-CD74 Rabbit Polyclonal Antibody (Cy5®)

Varenummer: (BOSSBS-4298R-CY5)
Leverandør: Bioss
Beskrivelse: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5328R-CY5

Anti-HTR3E Rabbit Polyclonal Antibody (Cy5®)

Varenummer: (BOSSBS-5328R-CY5)
Leverandør: Bioss
Beskrivelse: HTR3C belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5328R-CY3

Anti-HTR3E Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-5328R-CY3)
Leverandør: Bioss
Beskrivelse: HTR3C belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5328R

Anti-HTR3E Rabbit Polyclonal Antibody

Varenummer: (BOSSBS-5328R)
Leverandør: Bioss
Beskrivelse: HTR3C belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13141R-CY7

Anti-FANCD2 Rabbit Polyclonal Antibody (Cy7®)

Varenummer: (BOSSBS-13141R-CY7)
Leverandør: Bioss
Beskrivelse: Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
UOM: 1 * 100 µl
Image Unavailable-30988-50MG

Supelco® TraceCERT® Organic Reference Standard, Flutolanil

Varenummer: (30988-50MG)
Leverandør: Merck
Beskrivelse: The flutolanil CRM may also find following uses: Examine the reproductive endpoints on the gonad endocrine system of the parental zebrafish after chronic exposure to different concentrations of flutolanil for 60 days. Spectroscopic analysis of acetamiprid flutolanil and etofenprox residues extracted from tomato fruits. Development and validation of two robust chromatographic methods for estimation of tomatoes specific acetamiprid flutolanil and etofenprox residues on fruits before food processing and serving. To investigate the developmental toxicity and the potential mechanism of thyroid endocrine disruption induced by flutolanil in zebrafish embryos based on H¹ NMR metabolomics analysis. To develop a sensitive LC-MS/MS analytical method for the determination of residual flutolanil and its principal metabolites and conjugates in livestock and seafood products.
UOM: 1 * 50 mg
Image Unavailable-BOSSBS-6843R-CY3

Anti-MAGED1 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-6843R-CY3)
Leverandør: Bioss
Beskrivelse: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.
UOM: 1 * 100 µl
Image Unavailable-BNCB1090-100

Anti-HLA-DRA Mouse Monoclonal Antibody (Biotin) [clone: IPO-10]

Leverandør: Biotium
Beskrivelse: MAb IPO-10 defines the antigen, which appears on B cell progenitors following HLA-DR and preceding CD10, CD19, CD22, CD37 and cym. It is expressed on resting B cells and than reappears and persists in cytoplasm and on cell surface until cytoplasmic Ig appears. It is a useful antibody for diagnostics of neoplasms of B cell origins. It reacts with human B cell lines Daudi, Raji, Namalva, EB-3, RPMI-8226 (50% of cells). The MAb does not label T cell lines, blood granulocytes, thymocytes or bone marrow stromal fibroblasts. No significant changes are detected after PHA or ConA stimulation while LPS and PWM stimulated cultures after 18-48h show decreased number of antigen-positive cells but in final terms of cultivation antigen is expressed again. This MAb labels B cell leukemias and some lymphomas. Hairy cell leukemia strongly reacts and 70% of B cell CLL and some B-NHL were also positive. IPO-10 reacts with AMML cells and in a majority of Hodgkin's disease cases a significant percentage of affected lymph node cells were detected.

Image Unavailable-BNUB1090-500

Anti-HLA-DRA Mouse Monoclonal Antibody (Purified) [clone: IPO-10]

Leverandør: Biotium
Beskrivelse: MAb IPO-10 defines the antigen, which appears on B cell progenitors following HLA-DR and preceding CD10, CD19, CD22, CD37 and cym. It is expressed on resting B cells and than reappears and persists in cytoplasm and on cell surface until cytoplasmic Ig appears. It is a useful antibody for diagnostics of neoplasms of B cell origins. It reacts with human B cell lines Daudi, Raji, Namalva, EB-3, RPMI-8226 (50% of cells). The MAb does not label T cell lines, blood granulocytes, thymocytes or bone marrow stromal fibroblasts. No significant changes are detected after PHA or ConA stimulation while LPS and PWM stimulated cultures after 18-48h show decreased number of antigen-positive cells but in final terms of cultivation antigen is expressed again. This MAb labels B cell leukemias and some lymphomas. Hairy cell leukemia strongly reacts and 70% of B cell CLL and some B-NHL were also positive. IPO-10 reacts with AMML cells and in a majority of Hodgkin's disease cases a significant percentage of affected lymph node cells were detected.

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