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Image Unavailable-BOSSBS-2358R-A350

Anti-FOXA2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Varenummer: (BOSSBS-2358R-A350)
Leverandør: Bioss
Beskrivelse: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl
Image Unavailable-ENZOBML28330100

Protease inhibitor library, Screen-Well®

Leverandør: ENZO LIFE SCIENCES
Beskrivelse: The Screen-Well™ Protease Inhibitor Library includes 53 known protease inhibitors on a single 96-well plate. Inhibitors are supplied dissolved in DMSO at 10 mM and aliquoted into deep-well plates at either 100 or 500 microliters per well. The library includes inhibitors to a broad range of important proteases and is a convenient and cost-effective way to purchase a panel of protease inhibitors for chemical genomics, assay development, and other applications. It includes inhibitors of: Calpains, TPPII, Neutrophil Elastase, Cathepsins, DPPIV, Caspases, Granzyme B, gamma-Secretase, Furin, MMPs, ACE, Kallikrein, Proteasome, Aminopeptidase B, and many more.

Image Unavailable-BOSSBS-2358R-CY3

Anti-FOXA2 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-2358R-CY3)
Leverandør: Bioss
Beskrivelse: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2358R-A555

Anti-FOXA2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Varenummer: (BOSSBS-2358R-A555)
Leverandør: Bioss
Beskrivelse: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2358R-A750

Anti-FOXA2/HNF 3beta Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Varenummer: (BOSSBS-2358R-A750)
Leverandør: Bioss
Beskrivelse: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
UOM: 1 * 100 µl
Product Image-1.15973.0002

Iron hematoxylin kit (Weigert's) stain for histology, Sigma-Aldrich®

Varenummer: (1.15973.0002)
Leverandør: Merck
Beskrivelse: Nuclear staining in connective tissue staining methods
UOM: 1 * 2 Items

MSDS


Image Unavailable-PROONIST-612

Glass - trace elements, NIST standards

Leverandør: LGC Standards PROMOCHEM
Beskrivelse: This standard reference material is intended to facilitate the development of chemical methods of analysis for trace elements.

Image Unavailable-MDT100-1KT

Tissue Marking Dye Kit, Sigma-Aldrich®

Varenummer: (MDT100-1KT)
Leverandør: SIGMA ALDRICH MICROSCOPY
Beskrivelse: Designed for orientation of excised surgical specimens. This method of permanently marking the margins of tissue specimens is very beneficial to surgeon and pathologists testing for skin cancer.
UOM: 1 * 1 Each
Image Unavailable-PROOLGC7162

Standard reference material, strawberry leaves - trace elements

Varenummer: (PROOLGC7162)
Leverandør: LGC Standards PROMOCHEM
Beskrivelse: This standard is intended for use in development, validation and quality control of analytical methods for the determination of elements in vegetation.
UOM: 1 * 20 g
Product Image-ENZOENZ450140100

EpiXtract® total histone extraction kit

Varenummer: (ENZOENZ450140100)
Leverandør: ENZO LIFE SCIENCES
Beskrivelse: Rapid, reliable method to isolate histone proteins in mammalian cells and tissues for histone modification applications.
UOM: 1 * 1 Each
Image Unavailable-BOSSBS-8634R-HRP

Anti-FOXA1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Varenummer: (BOSSBS-8634R-HRP)
Leverandør: Bioss
Beskrivelse: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). Proposed to play a role in translating the epigenetic signatures into cell type-specific enhancer-driven transcriptional programs. Its differential recruitment to chromatin is dependent on distribution of histone H3 methylated at 'Lys-5' (H3K4me2) in estrogen-regulated genes. Involved in the development of multiple endoderm-derived organ systems such as liver, pancreas, lung and prostate; FOXA1 and FOXA2 seem to have at least in part redundant roles (By similarity). Modulates the transcriptional activity of nuclear hormone receptors. Is involved in ESR1-mediated transcription; required for ESR1 binding to the NKX2-1 promoter in breast cancer cells; binds to the RPRM promter and is required for the estrogen-induced repression of RPRM. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis.
UOM: 1 * 100 µl
Product Image-908-0066

Software for HPLC method development, ChromSwordAuto® 5 and ChromSwordAuto® 5 Hitachi Edition

Leverandør: COLLECTION PREFIX HPLC
Beskrivelse: ChromSwordAuto® 5: Communicates directly with the HPLC instrument in order to create a fully automated HPLC or UHPLC method development station. The unique ChromSwordAuto® software is capable of developing and optimising HPLC methods fully automatically within just a few hours. Methods already in use can also be optimised, thus reducing analysis time considerably. All you have to do is place the sample in the autosampler, set a few parameters and start the optimisation process. ChromSwordAuto® then predicts the method conditions and controls the HPLC system connected in recording the chromatograms. These are analysed by the software and the optimal conditions determined. The rapid optimisation mode can be used to provide an overview of the performance of the column/solvent system selected or to rapidly screen columns and eluents considered for use. The fine optimisation mode additionally collects and evaluates further ancillary data and produces up to 10 sets of alternative optimal HPLC conditions. Both of these operating modes can be applied in combination with column and solving switching procedures in order to try a variety of column/solvent combinations or to establish optimal pH conditions – fully automatically.
Main features include:

Image Unavailable-A-127-6X1.2ML

Multi-component alcohol mixture for calibration, Cerilliant®, Supelco®

Varenummer: (A-127-6X1.2ML)
Leverandør: Merck
Beskrivelse: A multicomponent calibration kit containing acetone, ethanol, isopropanol, and methanol at concentrations of 100, 250, 500, 1000, 2000, and 4000 μg/mL. This kit is suitable for calibration of blood alcohol testing methods using GC Headspace.
UOM: 1 * 6 Items
Product Image-1.04140.0001

Lateral Flow test for Salmonella, Singlepath® Salmonella

Varenummer: (1.04140.0001)
Leverandør: Merck
Beskrivelse: Most individuals infected with <i>Salmonella </i>develop diarrhea, fever, and abdominal cramps 12 to 72 H after infection. The illness usually lasts 4 to 7 days, and the majority of patients recover without treatment. However, in some cases, the diarrhea may be so severe that hospitalisation is required. <i>Salmonella</i> is a genus of rod-shaped, Gram-negative, non spore-forming, predominantly motile bacteria, belonging to the Enterobacteriaceae family.<i> Salmonella spp.</i> are one of the most common causes of food poisoning worldwide and have been isolated from most types of raw food (e.g. meats, eggs and plant products). Their high resistance to drying combined with a very high heat resistance once dried makes Salmonella a potential problem in most foods, particularly in dry and semi-dry products. Food legislation in many countries includes limits on Salmonella – typically absence in 25 g of food. Traditional microbiological methods for detection of <i>Salmonella</i> in food and animal feed require a total of up to five days to obtain a simple yes/no result. Innovative, rapid tests make screening for pathogenic organisms easier. The one-step format reduces the possibility of errors during handling.
UOM: 1 * 1 Each

MSDS


Image Unavailable-A-057-1.2ML

Multi-component alcohol mixtures for calibration, Cerilliant®, Supelco®

Leverandør: Merck
Beskrivelse: Multi-component calibration kits containing acetone, ethanol, isopropanol, and methanol varying concentrations. These kits ares suitable for calibration of blood alcohol testing methods using GC Headspace.

Product Image-ENZOENZ450160100

EpiXtract® Nuclear protein isolation kit

Varenummer: (ENZOENZ450160100)
Leverandør: ENZO LIFE SCIENCES
Beskrivelse: Rapid, reliable method to isolate nuclear proteins in mammalian cells and tissues.
UOM: 1 * 1 Each
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