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Avantor® ACE® C18-PFP, HPLC Columns, Microbore, 2 µm

Leverandør: Avantor

Beskrivelse: Avantor® ACE® C18-PFP phase utilises a specially developed ligand combining a C18 chain with integral PFP functionality. This results in a phase that maintains the hydrophobic, stability and low bleed characteristics of leading C18 phases, yet provides the multiple retention mechanisms of a PFP phase.

Mouse native NGF (from submaxillary glands)

Leverandør: Biosensis

Beskrivelse: Mouse NGF (2.5S) was isolated from mouse submaxillary glands by method of Mobley et al (1976) and is a form of beta-NGF that has identical biological properties. NGF is known to regulate the survival and development of certain sympathetic and sensory neurons. It is a dimer with 2 identical polypeptide chains and dimeric molecular weight of approximately 26,500 Da. Isolation and purification of NGF from mouse submaxillary glands yields preparations of NGF (2.5S) with identical biological activity but with cleavages at the amino terminus (with the loss of 8 amino acids) and/or at the carboxy-terminus (with the loss of arginine). These preparations are named 2.5 NGF.

Certifikater

Anti-proNGF Mouse Monoclonal Antibody (Biotin) [clone: BS312]

Varenummer: (BSENM-1778-50-B)

Leverandør: Biosensis

Beskrivelse: Nerve growth factor (NGF) is synthesized as a precursor (proNGF) which may be released and have physiological functions to cause cell death. It binds neurotrophin receptor p75 and sortilin and may also be important for the development of nervous system. proNGF is synthesized in target tissues and glia, transported retrogradely and may be released.

Biosensis' biotinylated proNGF antibody allowing more flexibility in experimental design by using the biotin-avidin/streptavidin detection method. The ability of biotinylated proNGF antibody to detect proNGF has been validated by WB.

UOM: 1 * 1 Each

Tilbud

N/A Each

Anti-FOXA2 Rabbit Polyclonal Antibody (Cy5®)

Varenummer: (BOSSBS-2358R-CY5)

Leverandør: Bioss

Beskrivelse: Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.

UOM: 1 * 100 µl

Tilbud