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Varenummer: (BOSSBS-5974R-FITC)

Leverandør: Bioss

Beskrivelse: SMYD3 is a gene that is over-expressed in the majority of colorectal carcinomas and hepatocellular carcinomas. SMYD3 forms a complex with RNA polymerase II through an interaction with the RNA helicase HELZ and transactivates a set of genes that included oncogenes, homeobox genes and genes associated with cell-cycle regulation. SMYD3 binds to a motif, 5'-CCCTCC-3', present in the promoter region of downstream genes such as Nkx2.8. The SET domain of SMYD3 shows histone H3-lysine 4 (H3-K4)-specific methyltransferase activity, which is enhanced in the presence of the heat-shock protein HSP90A.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-5389R-HRP)

Leverandør: Bioss

Beskrivelse: This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010].

UOM: 1 * 100 µl

Tilbud

Varenummer: (USBI042500)

Leverandør: US Biological

Beskrivelse: Anti-SUV420H1 Rabbit Polyclonal Antibody

UOM: 1 * 200 µl

Tilbud

Varenummer: (BOSSBS-9456R-A750)

Leverandør: Bioss

Beskrivelse: NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-9671R-HRP)

Leverandør: Bioss

Beskrivelse: ASH1L is a 2,969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-9671R-CY7)

Leverandør: Bioss

Beskrivelse: ASH1L is a 2,969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-9388R-CY7)

Leverandør: Bioss

Beskrivelse: The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription as well as mRNA degradation. Various subunits within the complex are involved in influencing nuclear hormone receptor activities. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome. CNOT8 (CCR4-NOT transcription complex subunit 8), also known as CALIF or POP2, is a 292 amino acid protein that localizes to both the nucleus and the cytoplasm and functions as part of the CCR-NOT complex. Expressed ubiquitously, CNOT8 plays a role in transcriptional regulation for a diverse set of processes.

UOM: 1 * 100 µl

Tilbud

Varenummer: (USBI031934-BIOTIN)

Leverandør: US Biological

Beskrivelse: Anti-KDM1B Rabbit Polyclonal Antibody (Biotin)

UOM: 1 * 200 µl

Tilbud

Varenummer: (BOSSBS-2891R-A750)

Leverandør: Bioss

Beskrivelse: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-10228R-CY7)

Leverandør: Bioss

Beskrivelse: The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012].

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-10228R-A488)

Leverandør: Bioss

Beskrivelse: The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumor suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012].

UOM: 1 * 100 µl

Tilbud

Leverandør: Thermo Fisher Scientific

Beskrivelse: (S)-Methyl-2-amino-6-(((benzyloxy)carbonyl)amino)hexanoate hydrochloride 95%

MSDS Certifikater

Leverandør: MP Biomedicals

Beskrivelse: Poly-L-Lysine is typically used as a coating substrate for culture dishes, slides, etc.

Varenummer: (J61903.AK)

Leverandør: Thermo Fisher Scientific

Beskrivelse: Running Buffer, IEF Cathode buffer (10X) with lysine

UOM: 1 * 250 mL

MSDS Certifikater Tilbud

Varenummer: (J63633.AC)

Leverandør: Thermo Fisher Scientific

Beskrivelse: Loading Buffer, IEF Sample Buffer (4X) with Lysine

UOM: 1 * 25 mL

MSDS Certifikater Tilbud

Varenummer: (USBI133593)

Leverandør: US Biological

Beskrivelse: Anti-SMYD2 Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Tilbud