Anti-CD24 Rat Monoclonal Antibody [clone: M1/69] (PerCP-Cy5.5)

Leverandør: STEMCELL Technologies
Ratings: Ingen bedømmelse

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Anti-CD24 Rat Monoclonal Antibody [clone: M1/69] (PerCP-Cy5.5)
Antistoffer
Rat monoclonal IgG2b antibody against mouse CD24, PerCP-Cy5.5-conjugated.

  • B cells
  • Mammary cells

The M1/69 antibody reacts with murine CD24, an ~35 - 45 kDa glycoprotein expressed on lymphocytes, granulocytes, thymocytes, erythrocytes, epithelial cells, neurons, and dendritic cells. CD24 is differentially expressed during T and B cell development, and is not found on the majority of mature peripheral T cells or plasma cells. It is expressed on pro-B, pre-B and mature B cells, but expression is strongly down-regulated after B cell activation. CD24 is involved in regulating B cell apoptosis and in preventing terminal differentiation of B cells into antibody-secreting plasmablasts and plasma cells. It acts as an adhesion or co-stimulatory molecule and is involved in lymphocyte activation, proliferation and differentiation through homophilic interactions or by binding to ligands such as P-selectin (CD62P).

Advarsel: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: CD24
Clonality: Monoclonal
Clone: M1/69
Conjugation: PerCP-Cy5.5
Epitope:
Host: Rat
Isotype: IgG2b kappa
Reactivity: Mouse
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