Anti-CD11b Rat Monoclonal Antibody [clone: M1/70] (APC)

Leverandør: STEMCELL Technologies
Ratings: Ingen bedømmelse

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Anti-CD11b Rat Monoclonal Antibody [clone: M1/70] (APC)
Antistoffer
Rat monoclonal IgG2b antibody against human, mouse, rhesus CD11b, APC-conjugated.

  • Granulocytes
  • Subsets
  • Monocytes

The M1/70 antibody reacts with CD11b, an ~170 kDa type 1 transmembrane glycoprotein which associates non-covalently with CD18 to form the heterodimeric Mac-1 receptor. Through its interactions with ligands such as ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen, Mac-1 functions in several processes, including the adherence of neutrophils and monocytes to stimulated endothelium and phagocytosis of complement-coatedMore Product Information
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