Anti-CD33 Mouse Monoclonal Antibody [clone: P67.6] (PE)

Leverandør: STEMCELL Technologies
Ratings: Ingen bedømmelse

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Anti-CD33 Mouse Monoclonal Antibody [clone: P67.6] (PE)
Antistoffer
Mouse monoclonal IgG1 antibody against human CD33, PE-conjugated.

  • Granulocytes
  • Subsets
  • Myeloid cells

The P67.6 antibody reacts with CD33 (Siglec-3), a 67 kDa type 1 transmembrane sialoadhesin protein of the immunoglobulin superfamily. CD33 is expressed on committed myeloid progenitor cells, monocytes, granulocytes, dendritic cells, mast cells, resident macrophages, subsets of B cells, and activated T and NK cells. CD33 is a major marker used to differentiate myeloid from lymphoid or erythroid leukemias. In peripheral blood, it is expressed at high levels on monocytes and at lower levels on granulocytes. CD33 functions as a sialic acid-dependent cell adhesion molecule and mediates protein-glycan and protein-protein interactions between cells. It also has a putative role as an inhibitory receptor during the immune response.

Advarsel: Product restrictions: (i) Customer shall not make products or any portion of them in any way, shape or form, including as a component of another product available for the purpose of further resale or alter or remove the Product label and the Supplier’s mark of origin without express written permission of Supplier and (ii) Customer is familiar with Supplier’s restrictions on the use of the products and shall use the products in compliance with such restrictions and the applicable Supplier Product Information sheet (collectively, the 'Product Restrictions').

Type:
Antigen: CD33
Clonality: Monoclonal
Clone: P67.6
Conjugation: PE
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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