Du Søgte efter: ProSci Inc.

Varenummer: (PRSIXP-5263)

Leverandør: ProSci Inc.

Beskrivelse: Anti-CD40L Goat Polyclonal Antibody

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSIXP-5257BT)

Leverandør: ProSci Inc.

Beskrivelse: RANTES is a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. It binds to CCR1, CCR3, CCR4 and CCR5 and is one of the major HIV suppressive factors produced by CD8+ T cells. Recombinant RANTES protein induces a dose dependent inhibition of different strains of HIV 1, HIV 2, and simian immunodeficiency virus (SIV). It is T cell and macrophage specific, induced by mitogens, and belongs to the intercrine beta (chemokine CC) family.

UOM: 1 * 1 Each

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Varenummer: (PRSI46-868)

Leverandør: ProSci Inc.

Beskrivelse: Anti-ABCC11 Goat Polyclonal Antibody

UOM: 1 * 1 Each

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Varenummer: (PRSIXP-5264)

Leverandør: ProSci Inc.

Beskrivelse: Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of mast cells and is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. It also mediates cell to cell adhesion and acts synergistically with other cytokines, probably interleukins. A soluble form is produced by proteolytic processing of isoform 1 in the extracellular domain.

UOM: 1 * 1 Each

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Varenummer: (PRSI29-315)

Leverandør: ProSci Inc.

Beskrivelse: PRKRA contains 3 DRBM (double-stranded RNA-binding) domains. It appears to have a pro-apoptotic function that may be suppressed in the presence of growth factor and activates EIF2AK2 in absence of double stranded RNA (dsRNA).

UOM: 1 * 1 Each

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Varenummer: (PRSI29-313)

Leverandør: ProSci Inc.

Beskrivelse: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.

UOM: 1 * 1 Each

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Varenummer: (PRSI29-303)

Leverandør: ProSci Inc.

Beskrivelse: SNRPA1 contains 3 LRR (leucine-rich) repeats and belongs to the U2 small nuclear ribonucleoprotein A family. It is associated with sn-RNP U2 and helps the A' protein to bind stem loop IV of U2 snRNA.

UOM: 1 * 1 Each

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Varenummer: (PRSI45-652)

Leverandør: ProSci Inc.

Beskrivelse: Anti-GALR1 Goat Polyclonal Antibody

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI29-900)

Leverandør: ProSci Inc.

Beskrivelse: ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis.

UOM: 1 * 1 Each

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Varenummer: (PRSI29-888)

Leverandør: ProSci Inc.

Beskrivelse: ADH4, class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole.This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI29-893)

Leverandør: ProSci Inc.

Beskrivelse: MTA2 modulates the enzymatic activity of the histone deacetylase core complex.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. This gene is found to be deleted in Williams syndrome.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI45-660)

Leverandør: ProSci Inc.

Beskrivelse: Anti-CCNDBP1 Goat Polyclonal Antibody

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI29-316)

Leverandør: ProSci Inc.

Beskrivelse: EIF3S9 binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI29-894)

Leverandør: ProSci Inc.

Beskrivelse: IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

UOM: 1 * 1 Each

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Varenummer: (PRSI30-614)

Leverandør: ProSci Inc.

Beskrivelse: The exact function of DKFZp779O175 remains unknown.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI31-313)

Leverandør: ProSci Inc.

Beskrivelse: SFRS12IP1 is a possible splicing regulator involved in the control of cellular survival.

UOM: 1 * 1 Each

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