Du Søgte efter: genome

Varenummer: (BOSSBS-5736R-A488)

Leverandør: Bioss

Beskrivelse: TACC2 is a conserved family of centrosome and microtubule interacting proteins that are implicated in cancer. This gene encodes a protein that concentrates at centrosomes throughout the cell cycle. This gene lies within a chromosomal region associated with tumorigenesis. Expression of this gene is thought to affect the progression of breast tumors. Expression of this gene is also induced by erythropoietin.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-8023R-A555)

Leverandør: Bioss

Beskrivelse: This gene belongs to the chemokine-like factor gene superfamily. This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-6545R)

Leverandør: Bioss

Beskrivelse: The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-6128R-CY5.5)

Leverandør: Bioss

Beskrivelse: This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. This gene is deleted in Williams-Beuren syndrome, adevelopmental disorder caused by deletion of multiple genes at 7q11.23.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-8128R-A750)

Leverandør: Bioss

Beskrivelse: This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. This gene is deleted in Williams-Beuren syndrome, adevelopmental disorder caused by deletion of multiple genes at 7q11.23.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-6165R-CY5)

Leverandør: Bioss

Beskrivelse: The KRAS gene encodes the human cellular homolog of a transforming gene isolated from the Kirsten rat sarcoma virus. The RAS proteins are GDP/GTP-binding proteins that act as intracellular signal transducers. The most well-studied members of the RAS (derived from 'RAt Sarcoma' virus) gene family include KRAS, HRAS, and NRAS. These genes encode immunologically related proteins with a molecular mass of 21 kD and are homologs of rodent sarcoma virus genes that have transforming abilities. While these wildtype cellular proteins in humans play a vital role in normal tissue signaling, including proliferation, differentiation, and senescence, mutated genes are potent oncogenes that play a role in many human cancers.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-8023R-A350)

Leverandør: Bioss

Beskrivelse: This gene belongs to the chemokine-like factor gene superfamily. This family of genes encodes multi-pass membrane proteins that are similar to both the chemokine and the transmembrane 4 superfamilies of signaling molecules. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-1342R-FITC)

Leverandør: Bioss

Beskrivelse: Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-9457R-A350)

Leverandør: Bioss

Beskrivelse: The protein encoded by this gene is a nuclear transcription factor involved in the activation of the solute carrier family 2 member 4 gene. The encoded protein interacts with another transcription factor, myocyte enhancer factor 2, to activate transcription of this gene. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-7619R-A750)

Leverandør: Bioss

Beskrivelse: This gene encodes a proline rich protein. Studies of the related mouse gene suggest that this gene is regulated by p53 and may participate in p53 mediated growth suppression. Alternatively spliced transcript variants encoding different isoforms have been described.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-7619R-A680)

Leverandør: Bioss

Beskrivelse: This gene encodes a proline rich protein. Studies of the related mouse gene suggest that this gene is regulated by p53 and may participate in p53 mediated growth suppression. Alternatively spliced transcript variants encoding different isoforms have been described.

UOM: 1 * 100 µl

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Varenummer: (USBII7662-94B-100)

Leverandør: US Biological

Beskrivelse: Anti-Interferon Stimulating Gene 15 Mouse Monoclonal Antibody [clone: 7G32]

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-8422R-FITC)

Leverandør: Bioss

Beskrivelse: This gene is located within a region of a segmental duplication on chromosome 16p. The product of this gene belongs to the eukaryotic subfamily of the BolA-like proteins. This gene encodes the BolA-like protein 2. The BolA-like proteins are widely conserved from prokaryotes to eukaryotes, and these proteins seem to be involved in cell proliferation or cell-cycle regulation. This duplicated region contains a complete copy of the short splice variant of the BOLA2 gene and a partial copy of the long splice variant of the BOLA2 gene.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-8422R-A647)

Leverandør: Bioss

Beskrivelse: This gene is located within a region of a segmental duplication on chromosome 16p. The product of this gene belongs to the eukaryotic subfamily of the BolA-like proteins. This gene encodes the BolA-like protein 2. The BolA-like proteins are widely conserved from prokaryotes to eukaryotes, and these proteins seem to be involved in cell proliferation or cell-cycle regulation. This duplicated region contains a complete copy of the short splice variant of the BOLA2 gene and a partial copy of the long splice variant of the BOLA2 gene.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-6072R-A680)

Leverandør: Bioss

Beskrivelse: This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-3322R-A350)

Leverandør: Bioss

Beskrivelse: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq].

UOM: 1 * 100 µl

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