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Varenummer: (ABNOPAB8444)

Leverandør: Abnova

Beskrivelse: Sheep polyclonal antibody raised against partial length recombinant vascular endothelial growth factor.

UOM: 1 * 10 mg

Tilbud

Varenummer: (BTIUBNUM1063-50)

Leverandør: Biotium

Beskrivelse: This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.

UOM: 1 * 50 µl

Tilbud

Leverandør: Shenandoah Biotechnology

Beskrivelse: Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) is an angiogenic growth factor that is expressed in the ovaries, testis, adrenal, and placental tissues. EG-VEGF has mitogenic, chemoattractive, and antiapoptotic functional roles.

Leverandør: Abcam

Beskrivelse: PE Rabbit monoclonal [001] to VEGF Receptor 2.

Leverandør: Abcam

Beskrivelse: Rabbit monoclonal [EPR28713-56] to VEGF Receptor 3 - BSA and azide free.

New Product

Varenummer: (ANTIA250834-100)

Leverandør: ANTIBODIES.COM

Beskrivelse: Rat monoclonal [DC101] antibody to VEGF Receptor 2 for WB and Neutralization Studies with samples derived from Mouse.

UOM: 1 * 1 Each

New Product Tilbud

Varenummer: (PRSI96-767)

Leverandør: ProSci Inc.

Beskrivelse: Vascular endothelial growth factor A (VEGFA) is also known as Vascular permeability factor (VPF). VEGFA belongs to the PDGF/VEGF growth factor family. VEGFA is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. VEGFA is produced by a group of three major isoforms as a result of alternative splicing and if any three isoforms are produced (VEGFA120, VEGFA164, and VEGFA188) then this will not result in vessel defects and death of the full VEGFA knockout in mice.

UOM: 1 * 1 Each

Tilbud

Varenummer: (PRSI96-772)

Leverandør: ProSci Inc.

Beskrivelse: VEGF165 is the most abundant splice variant of VEGF-A. VEGF165 is produced by a number of cells including endothelial cells, macrophages and T cells. VEGF165 is involved in angiogenesis, vascular endothelial cell survival, growth, migration and vascular permeability. VEGF gene expression is induced by hypoxia, inflammatory cytokines and oncogenes. VEGF165 binds to heparan sulfate and is retained on the cell surface and in the extracellular matrix. VEGF165 binds to the receptor tyrosine kinases, VEGFR1 and VEGFR2. VEGF165 is the only splice variant that binds to co-receptors NRP-1 and NRP-2 that function to enhance VEGFR2 signaling. Binding of VEGF165 to VEGFR1 and VEGFR2 leads to activation of the PI3K/AKT, p38 MAPK, FAK and paxillin. VEGF plays a key role in tumor angiogenesis in many cancers.

UOM: 1 * 1 Each

Tilbud

Varenummer: (BOSSBS-1586R-A488)

Leverandør: Bioss

Beskrivelse: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

UOM: 1 * 100 µl

Tilbud

Leverandør: Abcam

Beskrivelse: Rabbit monoclonal [EPR28328-80] to VEGF Receptor 2 - BSA and azide free.

New Product

Varenummer: (PRSI92-491)

Leverandør: ProSci Inc.

Beskrivelse: Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinase domain. VEGFR-1is an essential receptor tyrosine kinase and plays an important role in theregulation of VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. It is also mediators of neurotrophic activity and regulators of hematopoietic development. VEGFR-1 is a receptor for VEGF, VEGFB and PGF. It has a tyrosine-protein kinase activity. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF.It may play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells and promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. VEGFR-1 can also promote PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro).

UOM: 1 * 1 Each

Tilbud

Varenummer: (ANTIA307992-100)

Leverandør: ANTIBODIES.COM

Beskrivelse: Rabbit monoclonal [ARC0363] antibody to VEGF Receptor 1 for WB with samples derived from Mouse and Rat.

UOM: 1 * 100 µl

New Product Tilbud

Varenummer: (BSBTPA1080)

Leverandør: Boster Bio

Beskrivelse: Rabbit IgG polyclonal antibody for Vascular endothelial growth factor A (VEGFA) detection. Tested with WB, IHC-P in Human;Mouse;Rat.

UOM: 1 * 0,1 mg

Tilbud

Varenummer: (ANTIA254014-100)

Leverandør: ANTIBODIES.COM

Beskrivelse: Rat monoclonal [DC101] antibody to VEGF Receptor 2 for WB and Neutralization Studies with samples derived from mouse.

UOM: 1 * 1 Each

New Product Tilbud

Varenummer: (BOSSBS-1586R-A680)

Leverandør: Bioss

Beskrivelse: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-1586R-A350)

Leverandør: Bioss

Beskrivelse: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

UOM: 1 * 100 µl

Tilbud