Du Søgte efter: Overhead+omrørere

Varenummer: (BOSSBS-1213R-CY5)

Leverandør: Bioss

Beskrivelse: Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Regulates BIRC2 and BIRC3 protein levels by inhibiting their autoubiquitination and subsequent degradation; this does not depend on the TRAF2 RING-type zinc finger domain. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR. In complex with BIRC2 or BIRC3, promotes ubiquitination of IKBKE.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-3185R-CY5.5)

Leverandør: Bioss

Beskrivelse: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

UOM: 1 * 100 µl

Tilbud

Varenummer: (USBI036404-BIOTIN)

Leverandør: US Biological

Beskrivelse: Anti-H2AFX Rabbit Polyclonal Antibody (Biotin)

UOM: 1 * 200 µl

Tilbud

Varenummer: (USBIT8171-95D)

Leverandør: US Biological

Beskrivelse: Anti-TRAF2 Goat Polyclonal Antibody

UOM: 1 * 1 Each

Tilbud

Varenummer: (USBI029627)

Leverandør: US Biological

Beskrivelse: Anti-TRAF2 Rabbit Polyclonal Antibody

UOM: 1 * 1 Each

Tilbud

Varenummer: (USBIT8171-94C)

Leverandør: US Biological

Beskrivelse: Anti-TRAF2 Rabbit Polyclonal Antibody

UOM: 1 * 1 Each

Tilbud

Varenummer: (BOSSBS-8154R-CY5)

Leverandør: Bioss

Beskrivelse: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-8571R-CY5)

Leverandør: Bioss

Beskrivelse: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-8571R-CY7)

Leverandør: Bioss

Beskrivelse: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

UOM: 1 * 100 µl

Tilbud

Varenummer: (USBI043591-BIOTIN)

Leverandør: US Biological

Beskrivelse: Anti-UHRF2 Rabbit Polyclonal Antibody (Biotin)

UOM: 1 * 200 µl

Tilbud

Varenummer: (BOSSBS-1213R-CY3)

Leverandør: Bioss

Beskrivelse: Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Regulates BIRC2 and BIRC3 protein levels by inhibiting their autoubiquitination and subsequent degradation; this does not depend on the TRAF2 RING-type zinc finger domain. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR. In complex with BIRC2 or BIRC3, promotes ubiquitination of IKBKE.

UOM: 1 * 100 µl

Tilbud

Varenummer: (ABCAAB197031-100)

Leverandør: Abcam

Beskrivelse: Anti-U2AF65 Rabbit Monoclonal Antibody [clone: EPR17046]

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-8154R-CY7)

Leverandør: Bioss

Beskrivelse: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Tilbud

Varenummer: (USBI036402-BIOTIN)

Leverandør: US Biological

Beskrivelse: Anti-H2AFJ Rabbit Polyclonal Antibody (Biotin)

UOM: 1 * 200 µl

Tilbud

Varenummer: (ABCAAB213667-100)

Leverandør: Abcam

Beskrivelse: Anti-TRAF2 Rabbit Monoclonal Antibody [clone: EPR6048] (PE)

UOM: 1 * 100 µl

Tilbud

Varenummer: (USBI034888-FITC)

Leverandør: US Biological

Beskrivelse: Anti-E2F2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

UOM: 1 * 200 µl

Tilbud