Du Søgte efter: kappa-Carrageenan

Leverandør: Biotium

Beskrivelse: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Leverandør: Biotium

Beskrivelse: This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Varenummer: (BOSSBS-0627R-A647)

Leverandør: Bioss

Beskrivelse: Isoform 1: Acts as a transcriptional repressor. Inhibits erythroid differentiation and tumor cell proliferation. Plays a role during ovarian cancer development and progression. Isoform 2: Contributes to cervical carcinogenesis in part through the TNF-alpha-induced NF-kappa-B signaling pathway by interacting with the I-kappa-B-kinase (IKK) core complex.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-2029R)

Leverandør: Bioss

Beskrivelse: Morphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-7088R)

Leverandør: Bioss

Beskrivelse: Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases.

UOM: 1 * 100 µl

Tilbud

Varenummer: (ROCK709-1110)

Leverandør: Rockland Immunochemicals

Beskrivelse: Antibody Anti-Human IgG (kappa chain) is suitable for immunoblotting (western or dot blot), ELISA, and immunochemistry assays requiring lot-to-lot consistency.

UOM: 1 * 1 mg

Tilbud

Varenummer: (BOSSBS-2129R-HRP)

Leverandør: Bioss

Beskrivelse: Morphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-13399R-A750)

Leverandør: Bioss

Beskrivelse: Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, namely alpha, zeta, theta, kappa, mu, pi, sigma and omega, each of which are composed of proteins that have a variety of functions throughout the cell. GSTK1 (glutathione S-transferase kappa 1), also known as glutathione S-transferase subunit 13 (GST 13-13) or GSTK1-1, is a 226 amino acid ubiquitously expressed protein belonging to the kappa class of the GST superfamily that functions in cellular detoxification. Localizing to peroxisome, GSTK1 exists as a homodimer that catalyzes the conjugation of glutathione to a number of hydrophobic substrates leading to their removal from the cell.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-6066R-A488)

Leverandør: Bioss

Beskrivelse: Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-6066R-CY3)

Leverandør: Bioss

Beskrivelse: Heterodimers between TCF3 and tissue-specific basic helix-loop-helix (bHLH) proteins play major roles in determining tissue-specific cell fate during embryogenesis, like muscle or early B-cell differentiation. Dimers bind DNA on E-box motifs: 5'-CANNTG-3'. Binds to the kappa-E2 site in the kappa immunoglobulin gene enhancer.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-10123R)

Leverandør: Bioss

Beskrivelse: IKK Alpha/IKK beta is a member of the IKK complex which is composed of IKK alpha, IKK beta, IKK gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK beta has been shown to activate NF-kB and phosphorylate IKB alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK beta is essential for activation of IKK by TNF and IL1. Once activated, IKK beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK beta activity can also be regulated by MEKK1.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-0284R-CY5.5)

Leverandør: Bioss

Beskrivelse: Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.

UOM: 1 * 100 µl

Tilbud

Leverandør: CONTEC

Beskrivelse: These non pyrogenic LE wipes are the first sterile non woven wiping products designed for the pharmaceutical, medical device and biotech industries. Made with Sontara® lyocell/polyester blend fabric, these low endotoxin wipes have excellent sorbency and are packaged, gamma sterilised and validated sterile to a 10⁻⁶
Sterility Assurance Level.

Leverandør: Abcam

Beskrivelse: Rabbit monoclonal [EPR11633] to Human Kappa Chain - BSA and Azide free.

Leverandør: Abcam

Beskrivelse: Rabbit monoclonal [EPR23580-16] to Kappa light chain - BSA and Azide free (Detector).

Varenummer: (ABCAAB206198-500)

Leverandør: Abcam

Beskrivelse: Human IgG1, kappa - Isotype Control.

UOM: 1 * 1 Each

Tilbud