Du Søgte efter: genomer

Varenummer: (BOSSBS-13366R-A680)

Leverandør: Bioss

Beskrivelse: GK2 is a 553 amino acid protein that belongs to the FGGY kinase family and is involved in the pathway of glycerol degradation. Localized to the outer membrane of the mitochondrion and expressed at high levels in testis, GK2 functions to catalyze the ATP-dependent conversion of glycerol to glycerol 3-phosphate. Via its catalytic activity, GK2 plays an essential role in the regulation of glycerol uptake and metabolism. The gene encoding GK2 maps to chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-7687R)

Leverandør: Bioss

Beskrivelse: LAP3 (leucine aminopeptidase 3), also known as LAPEP or PEPS, is a 519 amino acid protein that localizes to the cytoplasm and belongs to the peptidase M17 family. Existing as a homohexamer, LAP3 uses zinc as a cofactor to catalyze the release of an N-terminal proline from a target peptide and is, therefore, involved in the processing and turnover of intracellular proteins. Multiple isoforms of LAP3 exist due to alternative splicing events. The gene encoding LAP3 maps to human chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-7687R-CY5)

Leverandør: Bioss

Beskrivelse: LAP3 (leucine aminopeptidase 3), also known as LAPEP or PEPS, is a 519 amino acid protein that localizes to the cytoplasm and belongs to the peptidase M17 family. Existing as a homohexamer, LAP3 uses zinc as a cofactor to catalyze the release of an N-terminal proline from a target peptide and is, therefore, involved in the processing and turnover of intracellular proteins. Multiple isoforms of LAP3 exist due to alternative splicing events. The gene encoding LAP3 maps to human chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-7687R-CY3)

Leverandør: Bioss

Beskrivelse: LAP3 (leucine aminopeptidase 3), also known as LAPEP or PEPS, is a 519 amino acid protein that localizes to the cytoplasm and belongs to the peptidase M17 family. Existing as a homohexamer, LAP3 uses zinc as a cofactor to catalyze the release of an N-terminal proline from a target peptide and is, therefore, involved in the processing and turnover of intracellular proteins. Multiple isoforms of LAP3 exist due to alternative splicing events. The gene encoding LAP3 maps to human chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-0338R)

Leverandør: Bioss

Beskrivelse: Hepatitis G virus is from a group of viruses called GB viruses (GB virus A, GB virus B and GB virus C) and is also designated as GB virus C (GBV C). HGV is a positive stranded RNA virus, with a genome of 10 KB and appears, on the basis of genome length and organisation, to be a member of the Flaviviridae and distinct from the hepatitis C virus (HCV). HGV infection appears to be transmitted following receipt of blood from HGV RNA positive donors, however, these patients have only moderate liver enzyme elevations and do not develop chronic liver disease.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-11627R-CY5)

Leverandør: Bioss

Beskrivelse: Fe65L is a 758 amino acid protein that contains one WW domain and two PID domains. Binding to the intracellular domain of the ∫-Amyloid precursor protein, Fe65L is thought to modulate the internalization and, therefore, the accessibility and function of ∫-Amyloid. Via its ability to control the intracellular accumulation of ∫-Amyloid, Fe65L is thought to play a role in the pathogenesis of Alzheimer's disease. Multiple isoforms of Fe65L exist due to alternative splicing events. The gene encoding Fe65L maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

UOM: 1 * 100 µl

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Leverandør: Merck

Beskrivelse: Optimized for the concentration and recovery of genomic DNA with SDS buffer. The low nonspecific binding characteristics of the membrane and the other device components, coupled with its medical-grade O-ring seal, allow the device to accommodate several wash steps with minimal sample loss.

Varenummer: (BOSSBS-7821R-A750)

Leverandør: Bioss

Beskrivelse: Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognising stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-0338R-CY3)

Leverandør: Bioss

Beskrivelse: Hepatitis G virus is from a group of viruses called GB viruses (GB virus A, GB virus B and GB virus C) and is also designated as GB virus C (GBV C). HGV is a positive stranded RNA virus, with a genome of 10 KB and appears, on the basis of genome length and organisation, to be a member of the Flaviviridae and distinct from the hepatitis C virus (HCV). HGV infection appears to be transmitted following receipt of blood from HGV RNA positive donors, however, these patients have only moderate liver enzyme elevations and do not develop chronic liver disease.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-0338R-A555)

Leverandør: Bioss

Beskrivelse: Hepatitis G virus is from a group of viruses called GB viruses (GB virus A, GB virus B and GB virus C) and is also designated as GB virus C (GBV C). HGV is a positive stranded RNA virus, with a genome of 10 KB and appears, on the basis of genome length and organisation, to be a member of the Flaviviridae and distinct from the hepatitis C virus (HCV). HGV infection appears to be transmitted following receipt of blood from HGV RNA positive donors, however, these patients have only moderate liver enzyme elevations and do not develop chronic liver disease.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-7821R-A647)

Leverandør: Bioss

Beskrivelse: Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-13549R-A488)

Leverandør: Bioss

Beskrivelse: he female gamete, the oocyte, serves the distinct purpose of transmitting the maternal genome and other maternal factors critical for postovulation events. Oocytes have diverse functions in ovarian folliculogenesis, fertilization, and embryogenesis. ZAR1 is an oocyte-specific gene that appears to function at the oocyte-to-gamete transition

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-9414R-A350)

Leverandør: Bioss

Beskrivelse: NET-4, also known as TSPAN5 or TM4SF9, is a 268 amino acid multi-pass membrane protein that belongs to the tetraspanin family and is thought to play a role in signal transduction events related to cell development, activation, growth and motility. The gene encoding NET-4 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-9414R-A647)

Leverandør: Bioss

Beskrivelse: NET-4, also known as TSPAN5 or TM4SF9, is a 268 amino acid multi-pass membrane protein that belongs to the tetraspanin family and is thought to play a role in signal transduction events related to cell development, activation, growth and motility. The gene encoding NET-4 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-2980R-FITC)

Leverandør: Bioss

Beskrivelse: Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-5634R-CY3)

Leverandør: Bioss

Beskrivelse: NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. Required for genomic stability. Regulates the production of TNF protein. Has a role in the regulation of life span (By similarity). Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. On DNA damage, promotes DNA end resection via deacetylation of RBBP8. Has very weak deacetylase activity and can bind NAD(+) in the absence of acetylated substrate.

UOM: 1 * 100 µl

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