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Image Unavailable-BOSSBS-4995R-A350

Anti-INSR Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Varenummer: (BOSSBS-4995R-A350)
Leverandør: Bioss
Beskrivelse: After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4995R-HRP

Anti-INSR Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Varenummer: (BOSSBS-4995R-HRP)
Leverandør: Bioss
Beskrivelse: After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3001R-CY7

Anti-ACIN1 Rabbit Polyclonal Antibody (Cy7®)

Varenummer: (BOSSBS-3001R-CY7)
Leverandør: Bioss
Beskrivelse: Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Component of the ASAP complexes which bind RNA in a sequence-independent manner and are proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets; ACIN1 confers RNA-binding to the complex. The ASAP complex can inhibit RNA processing during in vitro splicing reactions. The ASAP complex promotes apoptosis and is disassembled after induction of apoptosis. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the activity is different from the established EJC assembly and function. Induces apoptotic chromatin condensation after activation by CASP3. Regulates cyclin A1, but not cyclin A2, expression in leukemia cells.
UOM: 1 * 100 µl
Image Unavailable-USBIO8061-100

Osteoclast inhibitory lectin MAB MO XMO

Varenummer: (USBIO8061-100)
Leverandør: US Biological
Beskrivelse: Osteocrin is a recently identified secreted protein expression of which was only detected in bone, peaking just after birth and decreasing markedly with age. A 1280-bp mRNA encodes osteocrin producing a mature protein of 103 amino acids with a molecular mass of 11,4 kD. In primary osteoblastic cell cultures osteocrin expression coincided with matrix formation then decreased in very mature cultures.
UOM: 1 * 1 Each
Product Image-S0500-1000

Chicken serum

Leverandør: Biowest
Beskrivelse: Chicken serum is the liquid fraction of whole blood that is collected after the blood is allowed to clot; it is the blood plasma with the fibrinogens removed. Serum includes all proteins not used in blood clotting (coagulation) and all the electrolytes, antibodies, antigens, hormones, and any exogenous substances. Chicken serum is used as a blocking agent in immunoassays and controls.

MSDS Certifikater

Image Unavailable-M-250-1ML

Mycophenolic acid-O-β-D-glucuronide opløsning Acetonitrile:Water (90:10) (v/v) 1 mg/ml, Cerilliant®, certified reference material

Varenummer: (M-250-1ML)
Leverandør: Merck
Beskrivelse: Mycophenolic acid (MPA), the active moiety of the prodrug mycophenolate mofetil, is widely used in immunosuppressive regimens after kidney, liver or heart transplantation. MPA is metabolized predominantly to the inactive 7-O-glucuronide (MPAG). A minor fraction is converted to the pharmacologically active acyl glucuronide (AcMPAG). All compounds ultimately are eliminated via the kidneys.
UOM: 1 * 1 mL

New Product


Image Unavailable-BOSSBS-6843R

Anti-MAGED1 Rabbit Polyclonal Antibody

Varenummer: (BOSSBS-6843R)
Leverandør: Bioss
Beskrivelse: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1351R-A750

Anti-Granzyme B and Granzyme H Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Varenummer: (BOSSBS-1351R-A750)
Leverandør: Bioss
Beskrivelse: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1407R-FITC

Anti-H-1 beta Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-1407R-FITC)
Leverandør: Bioss
Beskrivelse: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
UOM: 1 * 100 µl
Image Unavailable-PBM2C-MON-1

Human M2 macrophages (monocyte derived) from peripheral blood

Leverandør: Charles River Laboratories Cell Solutions
Beskrivelse: Human peripheral blood M2 macrophages are derived from purified monocytes. CD14<sup>+</sup> monocytes were positively selected via immunomagnetic beads and were cultured in the presence of M-CSF for 10 days. The M2 phenotyping was confirmed by morphology and the expression of specific biomarkers which monitored by flow cytometry. The cells were harvested after 10 days of <i>in vitro </i>culture.

Image Unavailable-BOSSBS-6843R-CY3

Anti-MAGED1 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-6843R-CY3)
Leverandør: Bioss
Beskrivelse: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7725R-CY3

Anti-SA2 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-7725R-CY3)
Leverandør: Bioss
Beskrivelse: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6843R-A488

Anti-MAGED1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Varenummer: (BOSSBS-6843R-A488)
Leverandør: Bioss
Beskrivelse: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5328R-CY5.5

Anti-HTR3E Rabbit Polyclonal Antibody (Cy5.5®)

Varenummer: (BOSSBS-5328R-CY5.5)
Leverandør: Bioss
Beskrivelse: HTR3C belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2518R-CY5

Anti-CD74 Rabbit Polyclonal Antibody (Cy5®)

Varenummer: (BOSSBS-2518R-CY5)
Leverandør: Bioss
Beskrivelse: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2738R-CY3

Anti-FANCD2 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-2738R-CY3)
Leverandør: Bioss
Beskrivelse: Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation.DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
UOM: 1 * 100 µl
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