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Varenummer: (BOSSBS-6136R-A488)
Leverandør: Bioss
Beskrivelse: The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-2495R-HRP)
Leverandør: Bioss
Beskrivelse: Receptor for TNFSF8/CD3L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-2495R-A488)
Leverandør: Bioss
Beskrivelse: Receptor for TNFSF8/CD3L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-2495R-A750)
Leverandør: Bioss
Beskrivelse: Receptor for TNFSF8/CD3L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-2495R-A680)
Leverandør: Bioss
Beskrivelse: Receptor for TNFSF8/CD3L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-4029R-CY5.5)
Leverandør: Bioss
Beskrivelse: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-4778R-CY5)
Leverandør: Bioss
Beskrivelse: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B (By similarity).
UOM: 1 * 100 µl


Varenummer: (APOSBISN0074-50MG)
Leverandør: Apollo Scientific
Beskrivelse: BIBF0775 is an inhibitor of transforming growth factor β receptor I (TGFβRI) by soaking into the kinase domain of TGFβRI.
UOM: 1 * 50 mg


Varenummer: (BOSSBS-6817R-CY5.5)
Leverandør: Bioss
Beskrivelse: Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression.
UOM: 1 * 100 µl


Leverandør: Thermo Fisher Scientific
Beskrivelse: Lithium iodide hydrate is used as a reagent for ester cleavage and decarboxylation and C-C bond forming reactions. It is also used as source of nucleophilic iodide, as a mild lewis acid, epoxide opening and as an additive for organometallic-mediated transformations.
Varenummer: (BOSSBS-4029R-HRP)
Leverandør: Bioss
Beskrivelse: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-1684R-CY5.5)
Leverandør: Bioss
Beskrivelse: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-1684R-A647)
Leverandør: Bioss
Beskrivelse: SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-2969R)
Leverandør: Bioss
Beskrivelse: E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription (By similarity).
UOM: 1 * 100 µl


Varenummer: (BOSSBS-13115R-A680)
Leverandør: Bioss
Beskrivelse: Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-6136R-A350)
Leverandør: Bioss
Beskrivelse: The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11% of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105.
UOM: 1 * 100 µl


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