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Beskrivelse: Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI.Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers. In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth.
Varenummer: BOSSBS-2763R-CY5.5
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: Crk p38 (CrkII) is an isoform of the protein Crk. CrkI and CrkII are produced from the same crk gene by alternative splicing. The two isoforms differ in their biological activities with CrkII having less transforming activity than CrkI.Crk p38 is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. It has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Crk is believed to be a regulator of invasive responses because increased levels of the protein have been observed in multiple human cancers. In vivo studies have demonstrated that decreased levels of Crk remarkably inhibits tumor formation and its invasive growth.
Varenummer: BOSSBS-2763R-CY3
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression.
Varenummer: BOSSBS-6817R-A680
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression.
Varenummer: BOSSBS-6817R-HRP
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
Varenummer: BOSSBS-6385R-A750
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: NBL1 (Neuroblastoma, suppression of tumorigenicity 1) is a candidate tumor suppressor of neuroblastoma and may play a role in preventing cells from entering the final stage (G1/S) of the transformation process. NBL1 is a member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. It is a member of a class of glycoproteins shown to be secreted inhibitors of the transforming growth factor-beta (TGF-beta) and bone morphogenic protein pathways.
Varenummer: BOSSBS-6043R-FITC
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: NBL1 (Neuroblastoma, suppression of tumorigenicity 1) is a candidate tumor suppressor of neuroblastoma and may play a role in preventing cells from entering the final stage (G1/S) of the transformation process. NBL1 is a member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. It is a member of a class of glycoproteins shown to be secreted inhibitors of the transforming growth factor-beta (TGF-beta) and bone morphogenic protein pathways.
Varenummer: BOSSBS-6043R-A488
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
Varenummer: BOSSBS-6385R-A555
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion
Varenummer: BOSSBS-6223R-CY7
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: Minimum Essential Medium (MEM) with Earle’s Balanced Salts is a modification of Eagle’s earlier Basal Medium (BME) which contains a higher concentration of essential nutrients. These media promote the growth of a variety of normal and transformed cells. Since they contain Earle’s Balanced Salts, they are suitable for use in atmospheres charged with CO₂ gas.
Varenummer: 392-0424
UOM: 1 * 500 mL
Leverandør: VWR Chemicals

Beskrivelse: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion
Varenummer: BOSSBS-6223R-FITC
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion
Varenummer: BOSSBS-6223R-HRP
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion
Varenummer: BOSSBS-6223R-A488
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: DC1 slow acting decalcifiers contain a mixture of formic acid and formalin.
Varenummer: 11028303.
UOM: 1 * 5 L
Leverandør: VWR Chemicals

Beskrivelse: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion
Varenummer: BOSSBS-6223R-A647
UOM: 1 * 100 µl
Leverandør: Bioss


Beskrivelse: Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
Varenummer: BOSSBS-4029R-FITC
UOM: 1 * 100 µl
Leverandør: Bioss


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