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Product Image-705-0982

Turbiditetsmålere på bænk, TL23

Leverandør: Hach
Beskrivelse: Tungsten or LED light sources, as well as proven optics, make these instruments more reliable to deliver accurate and stable measurements.

Image Unavailable-BOSSBS-5791R-A750

Anti-Integrin Alpha V + Beta 6 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Varenummer: (BOSSBS-5791R-A750)
Leverandør: Bioss
Beskrivelse: Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha-v beta-6 is upregulated in cancers and during tissue remodelling but is absent from resting adult tissues. Integrin alpha-v beta-6 promotes invasion and correlates with poor survival and therefore makes a promising therapeutic target.
UOM: 1 * 100 µl
Image Unavailable-BNCB0176-100

Anti-CD5 Mouse Monoclonal Antibody (Biotin) [clone: Cris-1]

Leverandør: Biotium
Beskrivelse: Recognizes a 67 kDa transmembrane protein, which is identified as CD5 (HLDA I; WS Code T 29HLDA III; WS Code T 530). The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms.

Image Unavailable-BNC940791-500

Anti-ACTA2 Mouse Monoclonal Antibody (CF594) [clone: ACTA2/791]

Leverandør: Biotium
Beskrivelse: Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.

Image Unavailable-BOSSBS-9428R-A750

Anti-Tal1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Varenummer: (BOSSBS-9428R-A750)
Leverandør: Bioss
Beskrivelse: Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukaemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIalpha, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9428R-HRP

Anti-TAL1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Varenummer: (BOSSBS-9428R-HRP)
Leverandør: Bioss
Beskrivelse: Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIalpha, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors.
UOM: 1 * 100 µl
Image Unavailable-BNC401203-500

Anti-ACTA2 Mouse Monoclonal Antibody (CF640R) [clone: ACTA2/791 1A4]

Leverandør: Biotium
Beskrivelse: Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.

Image Unavailable-BTIUBNUM0791-50

Anti-ACTA2 Mouse Monoclonal Antibody (Purified, BSA-free) [clone: ACTA2/791]

Varenummer: (BTIUBNUM0791-50)
Leverandør: Biotium
Beskrivelse: Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
UOM: 1 * 50 µl
Image Unavailable-BOSSBS-3197R-CY7

Anti-IRS1 Rabbit Polyclonal Antibody (Cy7®)

Varenummer: (BOSSBS-3197R-CY7)
Leverandør: Bioss
Beskrivelse: Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.
UOM: 1 * 100 µl
Image Unavailable-BNC400883-100

Anti-KLK3 Mouse Monoclonal Antibody (CF640R) [clone: A67-B/E3]

Leverandør: Biotium
Beskrivelse: Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb 1A7G6B6 for PSA tests.

Image Unavailable-BOSSBS-9543R-A680

Anti-CCZ1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Varenummer: (BOSSBS-9543R-A680)
Leverandør: Bioss
Beskrivelse: Chromosome 7 is about 158 million bases long, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterised by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukaemia and myelodysplasia. The C7orf28 gene product has been provisionally designated C7orf28 pending further characterisation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3204R-A680

Anti-IRS1 Tyr896 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Varenummer: (BOSSBS-3204R-A680)
Leverandør: Bioss
Beskrivelse: Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3204R-FITC

Anti-IRS1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-3204R-FITC)
Leverandør: Bioss
Beskrivelse: Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3204R-CY3

Anti-IRS1 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-3204R-CY3)
Leverandør: Bioss
Beskrivelse: Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3204R-A647

Anti-IRS1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Varenummer: (BOSSBS-3204R-A647)
Leverandør: Bioss
Beskrivelse: Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3204R-CY5

Anti-IRS1 Rabbit Polyclonal Antibody (Cy5®)

Varenummer: (BOSSBS-3204R-CY5)
Leverandør: Bioss
Beskrivelse: Insulin receptor substrates (IRS) are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. Serine/threonine phosphorylation of IRS1 has been demonstrated to be a negative regulator of insulin signaling and is responsible for its degradation, although IRS1 degradation pathways are not well understood. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm's tumors, and adrenal cortical carcinomas, thus making IRS1 phosphorylation and subsequent degradation an attractive therapeutic target. To date there have been four subtypes identified: IRS1, 2, 3 and 4, with IRS1 being widely expressed.
UOM: 1 * 100 µl
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