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Leverandør: Biotium
Beskrivelse: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Leverandør: Biotium
Beskrivelse: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Leverandør: Biotium
Beskrivelse: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Leverandør: BURKLE
Beskrivelse: The sampling scoop can be used to take samples of powders, granulates and pastes. The long handle makes it possible to sample larger containers even with little content or to reach through narrow openings. With the straight bottom of the scoop, the medium can be scooped up directly from the bottom of the container.
Varenummer: (BOSSBS-3472R-A680)
Leverandør: Bioss
Beskrivelse: This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilising cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organiser of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.
UOM: 1 * 100 µl


Leverandør: ENZO LIFE SCIENCES
Beskrivelse: Actin is one of the major proteins (~42 kDa) of the cytoskeleton. It regulates contractile potential in muscle tissues and helps to control the shape as well as the motility of non-muscle cells. Actin is expressed in all eukaryotic cells which makes it a useful loading control in Western blotting experiments. In higher eukaryotes, there are six isoforms of actin: Three alpha-actins (α-skeletal, α-cardiac, α-smooth muscle), one β-actin (β-non-muscle) and two γ-actins (γ-smooth muscle and γ-non-muscle). Actin isoforms show >90% overall sequence homology.

Varenummer: (BOSSBS-15130R-CY5)
Leverandør: Bioss
Beskrivelse: The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf88 gene product has been provisionally designated C21orf88 pending further characterization.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-6798R-A350)
Leverandør: Bioss
Beskrivelse: Calpains are a family of cytosolic calcium activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin and cytoskeletal interactions, and synaptic plasticity. Calpain 12 was first described in the mouse, most strongly in the skin, and maps to mouse chromosome 7. Isoforms differ in the carboxyterminal ends, ending with aberrant domain III and lacking domain IV. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV, making Calpain 12 most similar to calpains 1 and 2.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-6798R-A555)
Leverandør: Bioss
Beskrivelse: Calpains are a family of cytosolic calcium activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin and cytoskeletal interactions, and synaptic plasticity. Calpain 12 was first described in the mouse, most strongly in the skin, and maps to mouse chromosome 7. Isoforms differ in the carboxyterminal ends, ending with aberrant domain III and lacking domain IV. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV, making Calpain 12 most similar to calpains 1 and 2.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-10138R)
Leverandør: Bioss
Beskrivelse: phrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. [provided by RefSeq, Jul 2008]
UOM: 1 * 100 µl


Varenummer: (331-0338)
Leverandør: BURKLE
Beskrivelse: The spoon with curved spoon bowl is suitable for a wide range of different media including powders, granulates, pastes and liquids. The angled spoon shape is also good for reaching into the corners of a container. The long handle of the plastic spoon makes it possible to empty residue from large containers easily and can also reach into places that are hard to reach such as jerrycans with narrow necks.
UOM: 1 * 10 Items


Varenummer: (BOSSBS-12549R-A680)
Leverandør: Bioss
Beskrivelse: Vacuolar-type H+-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1 domain, which is responsible for ATP hydrolysis, and a integral V0 domain, which is responsible for proton translocation, compose V-ATPase. Nine subunits (AH) make up the V1 domain and five subunits (a, d, c, c' and c") make up the V0 domain. Like F-ATPase, V-ATPase most likely operates through a rotary mechanism. The V-ATPase V1 B subunit exists as two isoforms. In the inner ear, the V-ATPase B1 isoform functions in proton secretion and is required to maintain proper endolymph pH and normal auditory function. The gene encoding the human V-ATPase B1 isoform maps to chromosome 2cen-q13. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. The V-ATPase B2 isoform is expressed in kidney and is the only B isoform expressed in osteoclasts. The gene encoding the human V-ATPase B2 isoform maps to chromosome 8p22-p21.
UOM: 1 * 100 µl


Leverandør: Hach
Beskrivelse: Tungsten or LED light sources, as well as proven optics, make these instruments more reliable to deliver accurate and stable measurements.

Varenummer: (90028.)
Leverandør: Biotium
Beskrivelse: APTS is a very useful green fluorescent dye for labeling glycoproteins or sugar molecules in general. The labeling occurs via reductive amination which involves the formation of a Schiff base between the amine of APTS and the aldehyde or ketone of the sugar, followed by the reduction of the Schiff base linkage to a stable carbon-nitrogen bond. The multi-anionic nature of the dye makes it ideal for the studies of carbohydrate molecules by high resolution capillary electrophoresis.
UOM: 1 * 10 mg


Varenummer: (223-0123)
Leverandør: BURKLE
Beskrivelse: In the withdrawal system for solvents with discharge hose, the barrel pump has a flexible discharge hose. The hose makes it possible to dispense the relevant solvent into tanks that are located some distance away and meter it accurately. With barrel screw connection for steel barrels with R 2" thread. Can be adjusted for standard commercial tanks with thread adapters.
UOM: 1 * 1 Items


Leverandør: VWR Collection
Beskrivelse: Polished granite. Four absorbing feet dampen the transmission of extraneous vibrations to this slab making it suitable, not only for high precision weighing, but also microscopy and other similar delicate instrumentation.

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