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Image Unavailable-BOSSBS-11604R-A488

Anti-SLC6A9 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Varenummer: (BOSSBS-11604R-A488)
Leverandør: Bioss
Beskrivelse: Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11604R-FITC

Anti-SLC6A9 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-11604R-FITC)
Leverandør: Bioss
Beskrivelse: Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11604R-A647

Anti-SLC6A9 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Varenummer: (BOSSBS-11604R-A647)
Leverandør: Bioss
Beskrivelse: Na+/Cl- dependent neurotransmitter transporters are a superfamily of transmembrane proteins that contain 12 membrane spanning regions (1). Specifically, the highly hydrophobic Na+/Cl- dependent glycine transporters (GlyT) are crucial for the termination of neurotransmission at glycinergic synapses (2,3). Two different GlyT genes encode GlyT2 and GlyT1, which exists as two isoforms produced by alternative splicing of the same gene located on human chromosome 1p31.3 (3,4). The GlyT1 gene may be an early marker of neural development and encodes glia-specific transporter proteins (3). Although GlyT1 and GlyT2 are both expressed in the brain and spinal cord, each shows a unique pattern of expression (3,5,6). GlyT1 is found only in the white matter of the CNS, whereas GlyT2 is found in the gray matter of the CNS as well as in macrophages and mast cells in peripheral tissues (3,5). The anatomic distribution of GlyT2 mRNA suggests that glycine may act as a supraspinal neurotransmitter and may function as a chemical messenger outside the CNS (5).
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13043R-CY3

Anti-DYX1C1 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-13043R-CY3)
Leverandør: Bioss
Beskrivelse: The gene encoding DYX1C1 maps in the 15q21 region, which is disrupted by a translocation t(2;15)(q11;q21) and segregates with dyslexia. Two sequence changes in DYX1C1, including one involving the translation initiation sequence and an Elk-1 transcription factor binding site (-3G -->A) and a codon (1249G -->T), introduce a premature stop codon and truncate the protein by 4 amino acids. DYX1C1 encodes a nuclear tetratricopeptide repeat domain protein that is dynamically regulated in brain. In human brain, DYX1C1 protein localizes to a fraction of cortical neurons and white matter glial cells. It is also expressed in lung, kidney and testis.
UOM: 1 * 100 µl
Product Image-DISI2022-1036

Single-use bioreactor systems, BIOne

Leverandør: DISTEK
Beskrivelse: Distek, Inc. has developed a bench top scale single-use bioreactor (SUB) for mammalian cell growth, cell therapy, insect cells and other unique applications performed in a stirred tank bioreactor. The gamma irradiated BIOne SUB is engineered with a disposable head plate welded to a triple-layered liner that can be easily inserted into a non sterile bioreactor glass vessel, converting it to a disposable SUB within a matter of seconds.

Image Unavailable-BOSSBS-5077R-CY5

Anti-CERS2 Rabbit Polyclonal Antibody (Cy5®)

Varenummer: (BOSSBS-5077R-CY5)
Leverandør: Bioss
Beskrivelse: LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5077R-A750

Anti-Ceramide synthase 2 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Varenummer: (BOSSBS-5077R-A750)
Leverandør: Bioss
Beskrivelse: LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localised to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5077R-CY7

Anti-CERS2 Rabbit Polyclonal Antibody (Cy7®)

Varenummer: (BOSSBS-5077R-CY7)
Leverandør: Bioss
Beskrivelse: LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5077R-CY3

Anti-CERS2 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-5077R-CY3)
Leverandør: Bioss
Beskrivelse: LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5077R-A680

Anti-Ceramide synthase 2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Varenummer: (BOSSBS-5077R-A680)
Leverandør: Bioss
Beskrivelse: LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localised to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13043R-A750

Anti-DYX1C1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Varenummer: (BOSSBS-13043R-A750)
Leverandør: Bioss
Beskrivelse: The gene encoding DYX1C1 maps in the 15q21 region, which is disrupted by a translocation t(2;15)(q11;q21) and segregates with dyslexia. Two sequence changes in DYX1C1, including one involving the translation initiation sequence and an Elk-1 transcription factor binding site (-3G --> A) and a codon (1249G --> T), introduce a premature stop codon and truncate the protein by 4 amino acids. DYX1C1 encodes a nuclear tetratricopeptide repeat domain protein that is dynamically regulated in brain. In human brain, DYX1C1 protein localizes to a fraction of cortical neurons and white matter glial cells. It is also expressed in lung, kidney and testis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13043R-A680

Anti-DYX1C1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Varenummer: (BOSSBS-13043R-A680)
Leverandør: Bioss
Beskrivelse: The gene encoding DYX1C1 maps in the 15q21 region, which is disrupted by a translocation t(2;15)(q11;q21) and segregates with dyslexia. Two sequence changes in DYX1C1, including one involving the translation initiation sequence and an Elk-1 transcription factor binding site (-3G --> A) and a codon (1249G --> T), introduce a premature stop codon and truncate the protein by 4 amino acids. DYX1C1 encodes a nuclear tetratricopeptide repeat domain protein that is dynamically regulated in brain. In human brain, DYX1C1 protein localizes to a fraction of cortical neurons and white matter glial cells. It is also expressed in lung, kidney and testis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13043R-A488

Anti-DYX1C1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Varenummer: (BOSSBS-13043R-A488)
Leverandør: Bioss
Beskrivelse: The gene encoding DYX1C1 maps in the 15q21 region, which is disrupted by a translocation t(2;15)(q11;q21) and segregates with dyslexia. Two sequence changes in DYX1C1, including one involving the translation initiation sequence and an Elk-1 transcription factor binding site (-3G -->A) and a codon (1249G -->T), introduce a premature stop codon and truncate the protein by 4 amino acids. DYX1C1 encodes a nuclear tetratricopeptide repeat domain protein that is dynamically regulated in brain. In human brain, DYX1C1 protein localizes to a fraction of cortical neurons and white matter glial cells. It is also expressed in lung, kidney and testis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7715R

Anti-RANBP9 Rabbit Polyclonal Antibody

Varenummer: (BOSSBS-7715R)
Leverandør: Bioss
Beskrivelse: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Involved in activation of androgen and glucocorticoid receptor in the presence of their cognate hormones. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.Tissue specificity: Ubiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the Purkinje cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7715R-CY7

Anti-RANBP9 Rabbit Polyclonal Antibody (Cy7®)

Varenummer: (BOSSBS-7715R-CY7)
Leverandør: Bioss
Beskrivelse: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Involved in activation of androgen and glucocorticoid receptor in the presence of their cognate hormones. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.Tissue specificity: Ubiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the Purkinje cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13043R-A647

Anti-DYX1C1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Varenummer: (BOSSBS-13043R-A647)
Leverandør: Bioss
Beskrivelse: The gene encoding DYX1C1 maps in the 15q21 region, which is disrupted by a translocation t(2;15)(q11;q21) and segregates with dyslexia. Two sequence changes in DYX1C1, including one involving the translation initiation sequence and an Elk-1 transcription factor binding site (-3G -->A) and a codon (1249G -->T), introduce a premature stop codon and truncate the protein by 4 amino acids. DYX1C1 encodes a nuclear tetratricopeptide repeat domain protein that is dynamically regulated in brain. In human brain, DYX1C1 protein localizes to a fraction of cortical neurons and white matter glial cells. It is also expressed in lung, kidney and testis.
UOM: 1 * 100 µl
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