Du Søgte efter: N-Boc-L-serine

Varenummer: (BOSSBS-9428R)

Leverandør: Bioss

Beskrivelse: Activation of TAL1 characterizes up to 60% of cases of human T cell acute lymphoblastic leukemia, making it the most frequent gain-of-function mutation observed in this disorder. TAL1 (also designated SCL) is a serine phosphoprotein and basic helix-loop-helix transcription factor known to regulate embryonic hematopoiesis. This transcription factor binds as a heterodimer with E2A and HEB/HTF4 to a nucleotide sequence motif termed the E-box. In addition, leukemogenesis is accelerated dramatically by transgenic co-expression of TAL1 and the catalytic subunit of casein kinase IIalpha, a serine/ threonine protein kinase known to modulate the activity of other bHLH transcription factors.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-9317R)

Leverandør: Bioss

Beskrivelse: Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-1655R-HRP)

Leverandør: Bioss

Beskrivelse: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.P21-activated kinase (PAK) is actually a family of serine/threonine protein kinases, members of which are activated by small molecular weight GTPases. The three most common isoforms are PAK 1, PAK 2, and PAK 3 (also known as alpha PAK, gamma PAK, and beta PAK, respectively). These kinases contain numerous regulatory elements that trigger diverse signaling processes such as those initiated by activated GTPases, interaction with Src homology 3 (SH3) domains, and caspase mediated proteolytic cleavage. Autophosphorylation of serine 141 (serine 144 for PAK 1 and serine 139 PAK 3), catalyzed by Cdc42, is required for activation of PAK.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-5777R-CY7)

Leverandør: Bioss

Beskrivelse: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BWRLBS4711)

Leverandør: Bioworld Technology

Beskrivelse: Synthetic phosphopeptide derived from human FKHR around the phosphorylation site of Serine 256.

UOM: 1 * 1 Each

Tilbud

Varenummer: (BOSSBS-7918R-A488)

Leverandør: Bioss

Beskrivelse: PLK5 (Serine/threonine-protein kinase PLK5) belongs to the protein kinase superfamily and Ser/Thr protein kinase family and CDC5/Polo subfamily. PLK5P contains 1 POLO box domain and 1 Serine/Threonine protein kinase catalytic domain.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-7918R-A555)

Leverandør: Bioss

Beskrivelse: PLK5 (Serine/threonine-protein kinase PLK5) belongs to the protein kinase superfamily and Ser/Thr protein kinase family and CDC5/Polo subfamily. PLK5P contains 1 POLO box domain and 1 Serine/Threonine protein kinase catalytic domain.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-7918R-CY5.5)

Leverandør: Bioss

Beskrivelse: PLK5 (Serine/threonine-protein kinase PLK5) belongs to the protein kinase superfamily and Ser/Thr protein kinase family and CDC5/Polo subfamily. PLK5P contains 1 POLO box domain and 1 Serine/Threonine protein kinase catalytic domain.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BWRLBS4600)

Leverandør: Bioworld Technology

Beskrivelse: Synthetic phosphopeptide derived from human p47-phox around the phosphorylation site of Serine 304.

UOM: 1 * 1 Each

Tilbud

Varenummer: (BWRLBS4106)

Leverandør: Bioworld Technology

Beskrivelse: Synthetic phosphopeptide derived from human IkB-beta around the phosphorylation site of Serine 23.

UOM: 1 * 1 Each

Tilbud

Varenummer: (BWRLBS4259)

Leverandør: Bioworld Technology

Beskrivelse: Synthetic phosphopeptide derived from human Na+/K+-ATPase alpha1 around the phosphorylation site of Serine 16.

UOM: 1 * 1 Each

Tilbud

Varenummer: (BOSSBS-9010R-FITC)

Leverandør: Bioss

Beskrivelse: DPP6 is a Type-II serine proteinase of the clan SC. The clan SC proteinases have a catalytic triad of Ser-Asp-His, and like other Serine proteinases, the active site serine is in a Gly-Xaa-Ser-Xaa -Gly orientation. DPP6 has an Asp instead of Ser in the catalytic site. DPP6 is a member of a broader family of dipeptidyl peptidases including DPP4, FAP/Seprase, DPP2, DPP8, DPP9, DPP10, which have differing substrate specificity and tissue localizations. The surface-bound DPP6 is a homodimer, and cleavage of in the stalk region releases a shed form of DPP6. The shed is the form found in serum. DPP6 has been found in highest abundance in the brain, but also in the kidney, liver and lung.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-9010R-HRP)

Leverandør: Bioss

Beskrivelse: DPP6 is a Type-II serine proteinase of the clan SC. The clan SC proteinases have a catalytic triad of Ser-Asp-His, and like other Serine proteinases, the active site serine is in a Gly-Xaa-Ser-Xaa -Gly orientation. DPP6 has an Asp instead of Ser in the catalytic site. DPP6 is a member of a broader family of dipeptidyl peptidases including DPP4, FAP/Seprase, DPP2, DPP8, DPP9, DPP10, which have differing substrate specificity and tissue localizations. The surface-bound DPP6 is a homodimer, and cleavage of in the stalk region releases a shed form of DPP6. The shed is the form found in serum. DPP6 has been found in highest abundance in the brain, but also in the kidney, liver and lung.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-0792R)

Leverandør: Bioss

Beskrivelse: Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BWRLBS4217)

Leverandør: Bioworld Technology

Beskrivelse: Synthetic phosphopeptide derived from human C/EBP alpha around the phosphorylation site of Serine 21.

UOM: 1 * 1 Each

Tilbud

Varenummer: (BWRLBS4652)

Leverandør: Bioworld Technology

Beskrivelse: Synthetic phosphopeptide derived from human AR-beta2 around the phosphorylation site of Serine 346.

UOM: 1 * 1 Each

Tilbud