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Image Unavailable-BOSSBS-0758R-A488

Anti-MSH2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Varenummer: (BOSSBS-0758R-A488)
Leverandør: Bioss
Beskrivelse: Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
UOM: 1 * 100 µl
Product Image-620-2317

Food Thermometer, HACCP, TLC 700

Varenummer: (620-2317)
Leverandør: EBRO
Beskrivelse: This folding thermometer is suitable for monitoring temperatures quickly and precisely, as required in incoming goods departments, for food distribution, for catering companies and for the food industry and trade, but also for monitoring temperatures in cold-storage warehouses or laboratories. The foldable penetration probe is used to measure the core temperature of food in particular.
UOM: 1 * 1 Items
Image Unavailable-BOSSBS-1384R-A555

Anti-ATG4B Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Varenummer: (BOSSBS-1384R-A555)
Leverandør: Bioss
Beskrivelse: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
UOM: 1 * 100 µl
Product Image-479-1898

Cap inserts for cryogenic vials, TruCool®

Leverandør: BIOCISION
Beskrivelse: TruCool®, Cryogenic vial cap insert, lilla, Ikke steril

Product Image-548-0029

VWR® ND9, Vials med kort gevind

Leverandør: VWR Collection
Beskrivelse: Standardvials i glas eller plast til GC og HPLC, mikroindsatser, låg og sæt. Universelt brugbare til næsten alle autosamplere, foretrukken vialtype til Waters og Agilent.

Product Image-612-4094

Coloured cap inserts, Capinsert™

Leverandør: Simport Scientific
Beskrivelse: CapInsert™, Coloured cap insert, PP, lyserød

Image Unavailable-BOSSBS-4041R

Anti-TALDO1 Rabbit Polyclonal Antibody

Varenummer: (BOSSBS-4041R)
Leverandør: Bioss
Beskrivelse: Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4041R-A680

Anti-Transaldolase 1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Varenummer: (BOSSBS-4041R-A680)
Leverandør: Bioss
Beskrivelse: Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4057R-HRP

Anti-ZBTB8A Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Varenummer: (BOSSBS-4057R-HRP)
Leverandør: Bioss
Beskrivelse: DEGS1 is a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. It contains three His containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It has sphingolipid-delta-4-desaturase activity and converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine).
UOM: 1 * 100 µl
Product Image-216-6903

Aluminium inserts for ice baths

Leverandør: KOEHLER TECHNISCHE PRODUKTEN
Beskrivelse: The inserts are simply mounted in the special groove.

Product Image-300-0022

Mælkepulveropsamler, Milky

Varenummer: (300-0022)
Leverandør: BURKLE
Beskrivelse: Rustfri stålkonstruktion. Udviklet til prøveudtagning af mælkepulver. Opsamleren indsættes i poser eller fade, og prøven fjernes ved hjælp af en halvskalformet lanse. Indføringsdybde 385 mm, total længde 480 mm, udvendig diameter ca. 28 mm.
UOM: 1 * 1 Items
Image Unavailable-BOSSBS-11710R-A555

Anti-BEAN1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Varenummer: (BOSSBS-11710R-A555)
Leverandør: Bioss
Beskrivelse: The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9521R-FITC

Anti-FECH Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-9521R-FITC)
Leverandør: Bioss
Beskrivelse: Ferrochelatase catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway, and is localised in the mitochondrion. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. Porphyrias are a group of inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway). They are broadly classified as hepatic porphyrias or erythropoietic porphyrias, based on the site of the overproduction and mainly accumulation of the porphyrins (or their chemical precursors). They manifest with either skin problems, or neurological complications, or occasionally both.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-9521R-HRP

Anti-FECH Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Varenummer: (BOSSBS-9521R-HRP)
Leverandør: Bioss
Beskrivelse: Ferrochelatase catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway, and is localised in the mitochondrion. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. Porphyrias are a group of inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway). They are broadly classified as hepatic porphyrias or erythropoietic porphyrias, based on the site of the overproduction and mainly accumulation of the porphyrins (or their chemical precursors). They manifest with either skin problems, or neurological complications, or occasionally both.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8542R-A555

Anti-MSH3 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Varenummer: (BOSSBS-8542R-A555)
Leverandør: Bioss
Beskrivelse: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8542R-A488

Anti-MSH3 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Varenummer: (BOSSBS-8542R-A488)
Leverandør: Bioss
Beskrivelse: Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
UOM: 1 * 100 µl
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