Du Søgte efter: genome

Varenummer: (BOSSBS-15019R-HRP)

Leverandør: Bioss

Beskrivelse: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf135 gene product has been provisionally designated C1orf135 pending further characterization.

UOM: 1 * 100 µl

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Varenummer: (BOSSBS-7094R-A750)

Leverandør: Bioss

Beskrivelse: This gene is specifically expressed in the thymus, and encodes a protein that is localised to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-15526R-A488)

Leverandør: Bioss

Beskrivelse: This gene encodes a protein that is similar to other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the expression of a similar gene to be increased after waking and sleep deprivation.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-15526R-A680)

Leverandør: Bioss

Beskrivelse: This gene encodes a protein that is similar to other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the expression of a similar gene to be increased after waking and sleep deprivation.

UOM: 1 * 100 µl

Tilbud

Varenummer: (USBIC0115-02Y)

Leverandør: US Biological

Beskrivelse: Anti-Calcitonin Gene-Related Peptide Rabbit Polyclonal Antibody

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-6928R)

Leverandør: Bioss

Beskrivelse: CCDC17, also known as FLJ17921 or RP4-697E16.4, is a 622 amino acid protein expressed as four isoforms and encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-6248R-A680)

Leverandør: Bioss

Beskrivelse: This gene encodes a member of the inositol monophosphatase family. The encoded protein is localised to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-6248R-CY3)

Leverandør: Bioss

Beskrivelse: This gene encodes a member of the inositol monophosphatase family. The encoded protein is localized to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). Mutations in this gene are a cause of GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of this gene is located on the long arm of chromosome 1.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-8024R-A555)

Leverandør: Bioss

Beskrivelse: This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene is widely expressed in many tissues, but the exact function of the encoded protein is unknown. [provided by RefSeq, Jul 2008].

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-3309R)

Leverandør: Bioss

Beskrivelse: This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009].

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-3308R)

Leverandør: Bioss

Beskrivelse: This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009].

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-6089R-CY5)

Leverandør: Bioss

Beskrivelse: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UOM: 1 * 100 µl

Tilbud

Varenummer: (BOSSBS-6007R-CY5)

Leverandør: Bioss

Beskrivelse: This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in three transcript variants encoding different isoforms.

UOM: 1 * 100 µl

Tilbud

Varenummer: (USBIC0115-02K)

Leverandør: US Biological

Beskrivelse: Anti-Calcitonin Gene Related Peptide Rabbit Polyclonal Antibody

UOM: 1 * 1 Each

Tilbud

Varenummer: (USBIP9102-71E)

Leverandør: US Biological

Beskrivelse: Anti-Protein Gene Product 9.5 Mouse Monoclonal Antibody [clone: 9i250]

UOM: 1 * 500 µl

Tilbud

Varenummer: (BOSSBS-3798R-CY7)

Leverandør: Bioss

Beskrivelse: Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors.

UOM: 1 * 100 µl

Tilbud