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Leverandør: Thermo Fisher Scientific
Beskrivelse: Ravsyre ≥99.0% ACS
Varenummer: (BOSSBS-12198R)
Leverandør: Bioss
Beskrivelse: JMJD2B is a 1,064 amino acid protein encoded by the human gene JMJD2B. JMJD2B belongs to the JMJD2B histone demethylase family and contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers and two Tudor domains. The two Tudor domains recognize and bind methylated histones and have an interdigitated structure; the unusual fold is required for its ability to bind methylated histone tails. JMJD2B is a histone demethylase that specifically demethylates Lys 9 residues of Histone H3, thereby playing a role in histone code. It does not demethylate Histone H3 Lys 4, H3 Lys 27, H3 Lys 36 or H4 Lys 20, however, and is only able to demethylate trimethylated H3 Lys-9 and has weaker activity than JMJD2A, JMJD2C and JMJD2D. JMJD2B demethyl-ation of Lysine residues will generate formaldehyde and succinate. JMJD2B is a ubiquitously expressed nuclear protein.
UOM: 1 * 100 µl


Leverandør: Thermo Fisher Scientific
Beskrivelse: N-Methyl-D-aspartic acid ≥98%
Leverandør: MERCK PRODUCTION CHEMICALS
Beskrivelse: Ravsyre 99.0-100.5% (by acidimetry), crystalline, EMPROVE® ESSENTIAL NF, ACS, JPE suitable for use as excipient, SAFC®
Varenummer: (471921000.)
Leverandør: Thermo Fisher Scientific
Beskrivelse: L-Chicoric acid 98%
UOM: 1 * 100 mg

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Varenummer: (BOSSBS-0532R)
Leverandør: Bioss
Beskrivelse: PHD3 (Egl nine homolog 3; Hypoxia-inducible factor prolyl hydroxylase 3; HIF-prolyl hydroxylase 3; HIF-PH3; HPH-1; Egln3; Prolyl hydroxylase domain-containing protein 3;)Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. May play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. Promotes cell death through a caspase-dependent mechanism. [Catalytic Activity] An HIF alpha chain L-proline + 2-oxoglutarate+ O(2) = An HIF alpha chain trans-4-hydroxy-L-proline + succinate + CO(2). [Subcellular Location] Cytoplasm. Nucleus. Widely expressed at low levels. Expressed athigher levels in heart (cardiac myocytes, aortic endothelial cells and coronary artery smooth muscle) and placenta.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-12200R)
Leverandør: Bioss
Beskrivelse: JMJD2B is a 1,064 amino acid protein encoded by the human gene JMJD2B. JMJD2B belongs to the JMJD2B histone demethylase family and contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers and two Tudor domains. The two Tudor domains recognize and bind methylated histones and have an interdigitated structure; the unusual fold is required for its ability to bind methylated histone tails. JMJD2B is a histone demethylase that specifically demethylates Lys 9 residues of Histone H3, thereby playing a role in histone code. It does not demethylate Histone H3 Lys 4, H3 Lys 27, H3 Lys 36 or H4 Lys 20, however, and is only able to demethylate trimethylated H3 Lys-9 and has weaker activity than JMJD2A, JMJD2C and JMJD2D. JMJD2B demethyl-ation of Lysine residues will generate formaldehyde and succinate. JMJD2B is a ubiquitously expressed nuclear protein.
UOM: 1 * 100 µl


Varenummer: (PRSI6879)
Leverandør: ProSci Inc.
Beskrivelse: SDHAF1 Antibody: SDHAF1 (Succinate dehydrogenase complex assembly factor 1) is one of the subunits of the succinate dehydrogenase (SDH) complex (or complex II) of the mitochondrial respiratory chain. SDHAF1 resides in the mitochondria, and is essential for SDH assembly, but does not physically associate with the complex in vivo. Mutations in this gene are associated with SDH-defective infantile leukoencephalopathy (mitochondrial complex II deficiency). Unlike the related protein SDHAF2, SDHAF1 is not thought to be a tumor suppressor.
UOM: 1 * 1 Each


Varenummer: (BSBTPA1839)
Leverandør: Boster Bio
Beskrivelse: Rabbit IgG polyclonal antibody for Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC) detection. Tested with WB, IHC-P in Human; Mouse; Rat.
UOM: 1 * 0,1 mg


Varenummer: (BSBTPA1717)
Leverandør: Boster Bio
Beskrivelse: Rabbit IgG polyclonal antibody for Succinate dehydrogenase[ubiquinone] flavoprotein subunit, mitochondrial (SDHA) detection. Tested with WB in Human; Mouse; Rat.
UOM: 1 * 0,1 mg


Varenummer: (PRSI25-899)
Leverandør: ProSci Inc.
Beskrivelse: SLC13A2 belongs to the SLC13A transporter (TC 2.A.47) family, NADC subfamily. It is a multi-pass membrane protein. SLC13A2 cotransports of sodium ions and dicarboxylates such as succinate and citrate.
UOM: 1 * 1 Each


Varenummer: (PRSI6847)
Leverandør: ProSci Inc.
Beskrivelse: SDHD Antibody: The mitochondrial succinate dehydrogenase complex subunit D (SDHD) is one of four proteins that make up the tricarboxylic cycle enzyme succinate dehydrogenase (SCH). Studies have shown that mutations in SDHD often leads to hereditary paragangliomas, usually benign tumors of the autonomic nervous system, suggesting that SDHD also plays a role as a tumor-suppressor gene. In one family with a nonsense mutation (R22X) in the SDHD gene, a loss of heterozygosity was found in the paragangliomas, and within these tumors the enzymatic activity of Complex II in the mitochondrial respiratory chain was completely abolished. Furthermore, high levels of angiogenic factors EPAS1 and VEGF was observed, which may stimulate tumor growth.
UOM: 1 * 1 Each


Varenummer: (BSBTPB9433)
Leverandør: Boster Bio
Beskrivelse: Rabbit IgG polyclonal antibody for Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human;Mouse;Rat.
UOM: 1 * 1 Each


Varenummer: (BSBTPA1718)
Leverandør: Boster Bio
Beskrivelse: Rabbit IgG polyclonal antibody for Succinate dehydrogenase[ubiquinone] iron-sulfur subunit, mitochondrial (SDHB) detection. Tested with WB, IHC-P in Human; Mouse; Rat.
UOM: 1 * 0,1 mg


Varenummer: (USBI123176)
Leverandør: US Biological
Beskrivelse: Anti-AKR7A2 Rabbit Polyclonal Antibody
UOM: 1 * 1 Each


Varenummer: (PRSI29-574)
Leverandør: ProSci Inc.
Beskrivelse: Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. SLC13A3 represents the high-affinity form.Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.
UOM: 1 * 1 Each


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