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Varenummer: (BOSSBS-15536R-FITC)
Leverandør: Bioss
Beskrivelse: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localises to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-15536R-CY5)
Leverandør: Bioss
Beskrivelse: Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localises to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-6728R-CY5.5)
Leverandør: Bioss
Beskrivelse: Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-6728R-A555)
Leverandør: Bioss
Beskrivelse: Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-5544R)
Leverandør: Bioss
Beskrivelse: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-5545R-CY5)
Leverandør: Bioss
Beskrivelse: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
UOM: 1 * 100 µl


Varenummer: (BWRLAP0484)
Leverandør: Bioworld Technology
Beskrivelse: Synthetic phosphopeptide derived from human ERK1/2 around the phosphorylation site of Threonine 202/Tyrosine 204.
UOM: 1 * 1 Each


Varenummer: (H66486.03)
Leverandør: Thermo Fisher Scientific
Beskrivelse: Fmoc-D-allo-thr(tBu)-OH 98%
UOM: 1 * 1 g

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Varenummer: (BOSSBS-6728R-CY3)
Leverandør: Bioss
Beskrivelse: Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
UOM: 1 * 100 µl


Varenummer: (BOSSBS-6728R-A350)
Leverandør: Bioss
Beskrivelse: Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
UOM: 1 * 100 µl


Varenummer: (BWRLAP0100)
Leverandør: Bioworld Technology
Beskrivelse: Synthetic phosphopeptide derived from human NPM around the phosphorylation site of Threonine 199.
UOM: 1 * 1 Each


Varenummer: (BWRLBS4457)
Leverandør: Bioworld Technology
Beskrivelse: Synthetic phosphopeptide derived from human AMPKalpha1 around the phosphorylation site of Threonine 183.
UOM: 1 * 1 Each


Varenummer: (BOSSBS-6728R-HRP)
Leverandør: Bioss
Beskrivelse: Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
UOM: 1 * 100 µl


Varenummer: (BWRLAP0291)
Leverandør: Bioworld Technology
Beskrivelse: Synthetic phosphopeptide derived from human PKC delta around the phosphorylation site of Threonine 505.
UOM: 1 * 1 Each


Varenummer: (BWRLBS4347)
Leverandør: Bioworld Technology
Beskrivelse: Synthetic phosphopeptide derived from human PKC zeta around the phosphorylation site of Threonine 560.
UOM: 1 * 1 Each


Varenummer: (BOSSBS-3785R-A350)
Leverandør: Bioss
Beskrivelse: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases). DRAKs contain an N terminal kinase domain and a C terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
UOM: 1 * 100 µl


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