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Image Unavailable-BOSSBS-4587R-CY5.5

Anti-IL6 Rabbit Polyclonal Antibody (Cy5.5®)

Varenummer: (BOSSBS-4587R-CY5.5)
Leverandør: Bioss
Beskrivelse: Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5145R-CY3

Anti-NPPB Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-5145R-CY3)
Leverandør: Bioss
Beskrivelse: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7725R

Anti-STAG2 Rabbit Polyclonal Antibody

Varenummer: (BOSSBS-7725R)
Leverandør: Bioss
Beskrivelse: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7725R-FITC

Anti-SA2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Varenummer: (BOSSBS-7725R-FITC)
Leverandør: Bioss
Beskrivelse: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7725R-HRP

Anti-SA2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Varenummer: (BOSSBS-7725R-HRP)
Leverandør: Bioss
Beskrivelse: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4298R-CY3

Anti-CD74 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-4298R-CY3)
Leverandør: Bioss
Beskrivelse: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5328R-CY7

Anti-HTR3E Rabbit Polyclonal Antibody (Cy7®)

Varenummer: (BOSSBS-5328R-CY7)
Leverandør: Bioss
Beskrivelse: HTR3C belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2518R-CY5.5

Anti-CD74 Rabbit Polyclonal Antibody (Cy5.5®)

Varenummer: (BOSSBS-2518R-CY5.5)
Leverandør: Bioss
Beskrivelse: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
UOM: 1 * 100 µl
Image Unavailable-BNC941090-100

Anti-HLA-DRA Mouse Monoclonal Antibody (CF594) [clone: IPO-10]

Leverandør: Biotium
Beskrivelse: MAb IPO-10 defines the antigen, which appears on B cell progenitors following HLA-DR and preceding CD10, CD19, CD22, CD37 and cym. It is expressed on resting B cells and than reappears and persists in cytoplasm and on cell surface until cytoplasmic Ig appears. It is a useful antibody for diagnostics of neoplasms of B cell origins. It reacts with human B cell lines Daudi, Raji, Namalva, EB-3, RPMI-8226 (50% of cells). The MAb does not label T cell lines, blood granulocytes, thymocytes or bone marrow stromal fibroblasts. No significant changes are detected after PHA or ConA stimulation while LPS and PWM stimulated cultures after 18-48h show decreased number of antigen-positive cells but in final terms of cultivation antigen is expressed again. This MAb labels B cell leukemias and some lymphomas. Hairy cell leukemia strongly reacts and 70% of B cell CLL and some B-NHL were also positive. IPO-10 reacts with AMML cells and in a majority of Hodgkin's disease cases a significant percentage of affected lymph node cells were detected.

Image Unavailable-BNUM1090-50

Anti-HLA-DRA Mouse Monoclonal Antibody (Purified, BSA-free) [clone: IPO-10]

Varenummer: (BNUM1090-50)
Leverandør: Biotium
Beskrivelse: MAb IPO-10 defines the antigen, which appears on B cell progenitors following HLA-DR and preceding CD10, CD19, CD22, CD37 and cym. It is expressed on resting B cells and than reappears and persists in cytoplasm and on cell surface until cytoplasmic Ig appears. It is a useful antibody for diagnostics of neoplasms of B cell origins. It reacts with human B cell lines Daudi, Raji, Namalva, EB-3, RPMI-8226 (50% of cells). The MAb does not label T cell lines, blood granulocytes, thymocytes or bone marrow stromal fibroblasts. No significant changes are detected after PHA or ConA stimulation while LPS and PWM stimulated cultures after 18-48h show decreased number of antigen-positive cells but in final terms of cultivation antigen is expressed again. This MAb labels B cell leukemias and some lymphomas. Hairy cell leukemia strongly reacts and 70% of B cell CLL and some B-NHL were also positive. IPO-10 reacts with AMML cells and in a majority of Hodgkin's disease cases a significant percentage of affected lymph node cells were detected.
UOM: 1 * 50 µl
Image Unavailable-BOSSBS-5328R-A555

Anti-HTR3E Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Varenummer: (BOSSBS-5328R-A555)
Leverandør: Bioss
Beskrivelse: HTR3C belongs to the ligand-gated ion channel receptor superfamily. HTR3E is a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4298R-A750

Anti-CD74 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Varenummer: (BOSSBS-4298R-A750)
Leverandør: Bioss
Beskrivelse: Plays a critical role in MHC class II antigen processing by stabilising peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6510R-A555

Anti-ALKBH8 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Varenummer: (BOSSBS-6510R-A555)
Leverandør: Bioss
Beskrivelse: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5394R-CY3

Anti-IL1R1 Rabbit Polyclonal Antibody (Cy3®)

Varenummer: (BOSSBS-5394R-CY3)
Leverandør: Bioss
Beskrivelse: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2787R-CY7

Anti-PSMB9 Rabbit Polyclonal Antibody (Cy7®)

Varenummer: (BOSSBS-2787R-CY7)
Leverandør: Bioss
Beskrivelse: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2787R-CY5

Anti-PSMB9 Rabbit Polyclonal Antibody (Cy5®)

Varenummer: (BOSSBS-2787R-CY5)
Leverandør: Bioss
Beskrivelse: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB6 by PSMB9 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues.
UOM: 1 * 100 µl
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