Du Søgte efter: 1-Thia-4-azaspiro[4.6]undecan-3-one

Beskrivelse: Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway dowstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.

Varenummer: BOSSBS-0724R

UOM: 1 * 100 µl

Leverandør: Bioss

Tilbud

Beskrivelse: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

Varenummer: BOSSBS-7697R

UOM: 1 * 100 µl

Leverandør: Bioss

Tilbud

Beskrivelse: Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

Varenummer: BOSSBS-7697R-CY5

UOM: 1 * 100 µl

Leverandør: Bioss

Tilbud

Beskrivelse: Chromatin reader that specifically recognises and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalises with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.

Varenummer: BOSSBS-7697R-A680

UOM: 1 * 100 µl

Leverandør: Bioss

Tilbud

Beskrivelse: Cell Meter™ No Wash and Probenecid-Free Endpoint Calcium Assay Kit enables homogeneous fluorescence-based assays for detecting intracellular calcium mobilization without the need to use kinetics reading mode.

Varenummer: AATB36312

UOM: 1 * 1 Each

Leverandør: AAT BIOQUEST

Tilbud

Beskrivelse: Helixyte™ Green dsDNA Quantitation Assay Kit can be used for selectively detecting as little as 25 pg/ml of dsDNA in the presence of ssDNA, RNA, and free nucleotides.

Varenummer: AATB17650

UOM: 1 * 1 Each

Leverandør: AAT BIOQUEST

Tilbud

Beskrivelse: Nitric oxide (NO) is an important biological regulator involved in numbers of physiological and pathological processes.

Varenummer: AATB16350

UOM: 1 * 1 Each

Leverandør: AAT BIOQUEST

Tilbud

Beskrivelse: Spare lamp for Biochrom EZ 800 Plus readers, Til: Asys Expert 96 and Asys Expert Plus

Varenummer: WAPRSB020009

UOM: 1 * 1 Items

Leverandør: Biochrom

Tilbud

Beskrivelse: The Neogen® Petrifilm® Plate Reader Advanced enumerates 11 different Neogen® Petrifilm Plates: Rapid Aerobic Count Plate, Rapid Coliform Count Plate, Rapid E. coli/Coliform Count Plate, Rapid Yeast and Mold Count Plate, Aerobic Count Plate, Coliform Count Plate, Enterobacteriaceae Count Plate, E. coli/Coliform Count Plate, Select E. coli Count Plate, Staph Express Count Plate, Staph Express Disk, and Lactic Acid Bacteria Count Plate.

Varenummer: 710-2148

UOM: 1 * 1 Items

Leverandør: 3M Food Safety

Tilbud

Beskrivelse: EarlyTox™ Cell Viability Assay Kits are a family of fluorescence-based reagents for the assessment of cell viability, cell proliferation, and various apoptosis events using mammalian cells. Optimised for use with microplate readers, these assay kits employ a no-wash, homogeneous assay protocol that enables characterisation of a full concentration-response profile of test compounds.

Varenummer: MLDVR8340

UOM: 1 * 1 Each

Leverandør: Molecular Devices

Tilbud

Beskrivelse: SmartChemical RFID Reader, Til: Mettler titrators

Varenummer: 661-0273

UOM: 1 * 1 Items

Leverandør: Mettler - Toledo

Tilbud

Beskrivelse: LogStraight™ finger print reader, Til: SevenExcellence™ meters

Varenummer: METT51192107

UOM: 1 * 1 Items

Leverandør: Mettler - Toledo

Tilbud

Beskrivelse: MUGlcU is a fluorogenic MU substrate for detecting glucuronidase in cell extracts and purified enzyme preparations using a fluorescence microplate reader or fluorometer.

Varenummer: AATB14016

UOM: 1 * 5 mg

Leverandør: AAT BIOQUEST

Tilbud

Beskrivelse: Lampe, 8V / 50W, Til: Multiskan EX

Varenummer: 735-0449

UOM: 1 * 1 Items

Leverandør: THERMO LABSYSTEMS LIFE SCIENCE

Tilbud

Beskrivelse: OPD (o-phenylenediamine dihydrochloride) is a water-soluble substrate for horseradish peroxidase (HRP) that produces a yellow-orange product detectable at 492 nm by ELISA plate readers.

Varenummer: PIER34006

UOM: 1 * 1 Each

Leverandør: Thermo Fisher Scientific

Tilbud

Beskrivelse: Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated PCNA that enhances RAD18-mediated PCNA ubiquitination and translesion DNA synthesis (TLS). Recruited to sites of UV damage and interacts with ubiquitinated PCNA and RAD18, the E3 ubiquitin ligase that monoubiquitinates PCNA. Facilitates chromatin association of RAD18 and is required for efficient PCNA monoubiquitination, promoting a feed-forward loop to enhance PCNA ubiquitination and translesion DNA synthesis. Acts as a regulator of TLS by recruiting VCP/p97 to sites of DNA damage, possibly leading to extraction of DNA polymerase eta (POLH) by VCP/p97 to prevent excessive translesion DNA synthesis and limit the incidence of mutations induced by DNA damage.

Varenummer: BOSSBS-15013R-A350

UOM: 1 * 100 µl

Leverandør: Bioss

Tilbud