TOYOPEARL® Super A Affinity Chromatography Protein Resins

Leverandør: TOSOH Bioscience
Ratings: Ingen bedømmelse

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TOYOPEARL® Super A Affinity Chromatography Protein Resins
Protein oprensnings Protein Purification Resins

TOYOPEARL® Super A resin provides a cutting-edge experience in protein A media, blending top-tier critical performance attributes with exceptional operational flexibility. An efficient and durable protein A resin.



  • State-of-the-art operational flexibility

  • Supports high titers with high dynamic binding capacity (DBC)

  • Enhanced alkaline stability for rigorous CIP

  • Excellent pressure flow behavior to increase process efficiency

  • Superior critical process performance

  • Features mild elution conditions

  • Reduction in process impurities, makes process robust, safe, and compliant


An enhanced, animal-origin free, recombinant protein A ligand is bound to the polymethacrylate base bead via multipoint attachment resulting in excellent base stability for up to 100 CIP cycles with 0,5 mol/L NaOH and up to 70 CIP cycles with 1 mol/L NaOH while maintaining 90% of its initial DBC.



TOYOPEARL Super A resin is available in ~45 µm particle size (F-grade) and exhibits dynamic binding capacities of greater than 70 g/L at 5 min residence time and greater than 60 g/L at 3 min residence time.



Improved mass transfer characteristics allow it to maintain a larger percent of its capacity at lower residence times relative to comparable agarose-based resins. It is therefore ideally suited for continuous operation using multiple short columns.



This resin is also available in pre-packed Skill Pak columns to simplify your process development and scale-up.



Bacterial count: max 100 CFU/ml

Endotoxin concentration: max 10 EU/ml

Delivery conditions: 72% slurry in 20% ethanol


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