Sulindac Sulphide ≥99% (by TLC)
Leverandør: ENZO LIFE SCIENCESSamlet vurdering
Gennemsntilig vurdering
Active metabolite of sulindac. Inhibits cyclooxygenase. More selective for PGHS-1 (ID50=0.5 µM) over PGHS-2 (ID50=14 µM). Induces apoptosis by a cyclooxygenase-independent mechanism. Inhibits colorectal cancer growth and γ-secretase. NF-κB inhibitor. Inhibits Ras signaling.
- COX inhibitor
Yellow-orange solid.
Soluble in DMSO (>25mg/ml) or 100% ethanol (5mg/ml, warm).
Formel:
C₂₀H₁₇FO₂S Molekylvægt: 340.4 g/mol Opbevaringstemperatur: Stue temperatur |
MDL Number:
MFCD00869764 CAS-nummer: 32004-67-4 |
Learn more

About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...