Necrostatin-5 ≥98% (by NMR)
Leverandør: ENZO LIFE SCIENCESSamlet vurdering
Gennemsntilig vurdering
Synonymer:
2-((3-(4-Methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetonitrile
Necroptosis inhibitor
Necroptosis inhibitor. In contrary to the mechanism of necrostatin-1 (Prod.No. BML-AP309) it was shown that necrostatin-5 inhibits RIP1 kinase indirectly. A potent inhibitor of immunoprecipitated, but not recombinant RIP1.
Formel:
C₁₉H₁₇N₃O₂S₂ |
CAS-nummer:
337349-54-9 |
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