trans-Ned-19
Leverandør: ENZO LIFE SCIENCESSamlet vurdering
Gennemsntilig vurdering
Cell permeable, selective and potent inhibitor of nicotinic acid adenine dinucleotide phosphate (NAADP) receptor in mammalian cells and sea urchin eggs. Blocks NAADP signaling. Inhibits Ca2+ release: trans-Ned-19 (IC50 = 6nM); cis-Ned-19 (IC50 = 800nM). [32P] NAADP binding: trans-Ned-19 (IC50 = 0.4nM); cis-Ned-19 (IC50 = 15µM).
Inhibits Ca2+ release from lysosomes. Noncompetitive antagonist. Fluorescent.
Synthetic
Formel:
C₃₀H₃₁FN₄O₃ Molekylvægt: 514.601 g/mol |
MDL Number:
MFCD02057367 CAS-nummer: 1354235-96-3 |
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