RK-682 ≥98% (by HPLC)

Leverandør: ENZO LIFE SCIENCES
Ratings: Ingen bedømmelse

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BMLPR1120200 BMLPR1121000
ENZOBMLPR1120200EA 1010 DKK
ENZOBMLPR1120200 ENZOBMLPR1121000
RK-682 ≥98% (by HPLC)
RK-682

RK-682 is a novel tyrosine phosphatase inhibitor isolated from Streptomyces sp. It inhibits the dual specificity VHR phosphatase (IC50=2.0µM) selectively over CD45 (IC50=54µM), Cdc25B and PTP1B (IC50~42µM). RK-682 inhibits cell cycle progression of Ball-1 cells at the G1/S transition and enhances ATP-induced long-term potentiation in guinea pig hippocampal CA1 neurons. Shows potent activity against HIV-1 protease.


  • VHR inhibitor


Pale yellow solid.


Soluble in DMSO (25mg/ml), 100% ethanol (10mg/ml), methanol or dimethyl formamide.

Formel: C₂₁H₃₆O₅
Opbevaringstemperatur: Fryser
CAS-nummer: 154639-24-4
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=fdf77141374c0b4b9fae52e7fe9c028afdfc5d3f&vid=f21724305c001ce7ebde5b4986fac1439627a5c3&prid=web&clid=SAPDAM

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