QS11 ≥98% (by HPLC)
Leverandør: ENZO LIFE SCIENCESSamlet vurdering
Gennemsntilig vurdering
Wnt pathway activator
Synergizers with Wnt3a to activate the Wnt/β-catenin pathway. Binds and inhibits GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1), thus activating ARF. It has also been suggested that a possible mechanism by which QS11 synergizes Wnt is through ARFGAP1 inhibition leading to increased β-catenin translocation via ARF activation.
Formel:
C₃₅H₃₃N₅O₂ |
MDL Number:
MFCD18086864 CAS-nummer: 944328-88-5 |
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