2-Methoxyestradiol ≥95%
Leverandør: ENZO LIFE SCIENCESSamlet vurdering
Gennemsntilig vurdering
Synonymer:
(8R,9S,13S,14S,17S)-2-Methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
Estrogen receptor inhibitor
An endogenous estrogen metabolite with low affinity for the estrogen receptor but which disrupts microtubule function. Potent inhibitor of endothelial cell proliferation and migration. Inhibits bFGF and VEGF-induced corneal neovascularization in mice. Posttranscriptionally downregulates HIF-1alpha expression.
Formel:
C₁₉H₂₆O₃ Molekylvægt: 302.408 g/mol |
MDL Number:
MFCD00010489 CAS-nummer: 362-07-2 |
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