N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Leverandør: Apollo Scientific
Ratings:
Ingen bedømmelse
Samlet vurdering
Gennemsntilig vurdering
Synonymer:
Gefitinib
BISN0101-1G
BISN0101-5G
APOSBISN0101-1GEA
1040
DKK
APOSBISN0101-1G
APOSBISN0101-5G
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Gefitinibis an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively, and interrupts signaling through the epidermal growth factor receptor (EGFR) in target cells.
Formel:
C₂₂H₂₄ClFN₄O₃ Smeltepunkt: 196 °C Opbevaringstemperatur: Køleskab |
MDL Number:
MFCD04307832 CAS-nummer: 184475-35-2 |
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