Cystaminiumdichlorid ≥95%, crystalline solid

Leverandør: Cayman Chemical
Ratings: Ingen bedømmelse

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Synonymer: Cystaminium dichloride, 2,2′-Diaminodiethyl disulphide dihydrochloride, 2,2'-Disulphanediyldiethanamine dihydrochloride, Bis(2-aminoethyl) disulphide dihydrochloride, Decarboxycystine dihydrochloride, Cystamine (dihydrochloride), {2-[(2-Aminoethyl)disulphanyl]ethyl}amine dihydrochloride, 2,2′-Dithiobis(ethylamine) dihydrochloride

14882-100 14882-25 14882-50 14882-500
CAYM14882-100EA 1690 DKK
CAYM14882-100 CAYM14882-25 CAYM14882-50 CAYM14882-500
Cystaminiumdichlorid ≥95%, crystalline solid
Cystaminiumdichlorid

Cystamine is an organic disulfide that inhibits TGM2 with an IC50 value of approximately 2.5 mM.


It is orally available and is neuroprotective in mouse models of Huntington’s disease. Cystamine also inhibits caspase 3, increases intracellular glutathione, and reduces inflammation in a rat model of inflammatory bowel disease.


Tissue transglutaminase (TGM2) post-translationally modifies proteins by catalyzing intermolecular cross-linkages between glutamine and lysine side chains. TGM2 has roles in neurodegenerative disorders, celiac sprue, cancer, and fibrotic diseases.

Formel: C₄H₁₂N₂S₂·2HCl
Molekylvægt: 225.20 g/mol
Opbevaringstemperatur: Fryser
MDL Number: MFCD00012905
CAS-nummer: 56-17-7

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