Verapamil hydrochloride ≥98%

Leverandør: Cayman Chemical
Ratings: Ingen bedømmelse

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Synonymer: 5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-(3,4-dimethoxyphenyl)-2-isopropylpentanenitrile hydrochloride, Verapamil HCl, 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile Hydrochloride, (±)-Verapamil hydrochloride

14288-1 14288-5
CAYM14288-1EA 615 DKK
CAYM14288-1 CAYM14288-5
Verapamil hydrochloride ≥98%
Verapamil hydrochloride

Verapamil is the prototypical blocker of L-type calcium channels that produces excitation-contraction uncoupling in cardiac muscle by preventing the slow-inward current of calcium ions.


Verapamil can also block calcium fluxes in vascular smooth muscle. It has both peripheral and coronary vasodilator effects (IC50=0,38 μm in guinea pig aortic strip) and has been used to control hypertension, angina, cardiac arrhythmia, and vascular headaches. Verapamil has also been used in cell biology as an inhibitor of drug efflux pump proteins such as P-glycoprotein, which are often over-expressed in certain tumor cell lines.

Formel: C₂₇H₃₈N₂O₄
Opbevaringstemperatur: Fryser
MDL Number: MFCD00055208
CAS-nummer: 152-11-4

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