Anti-CD2 Mouse Monoclonal Antibody (Biotin) [clone: HuLy-m1]

Leverandør: Biotium
Ratings: Ingen bedømmelse

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BNCB1053-500 BNCB1053-100
BNCB1053-500EA 4180 DKK
BNCB1053-500 BNCB1053-100
Anti-CD2 Mouse Monoclonal Antibody (Biotin) [clone: HuLy-m1]
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CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Type: Primary
Antigen: CD2
Clonality: Monoclonal
Clone: HuLy-m1
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Cat, Human
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