Anti-MS4A1 Mouse Monoclonal Antibody (CF640R) [clone: 93-1B3]

Leverandør: Biotium
Ratings: Ingen bedømmelse

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BNC401047-500 BNC401047-100
BNC401047-500EA 4180 DKK
BNC401047-500 BNC401047-100
Anti-MS4A1 Mouse Monoclonal Antibody (CF640R) [clone: 93-1B3]
Antistoffer
Recognizes a protein of 30-33 kDa, which is identified as CD20 (Workshop V; Code CD20.4). It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.

Type: Primary
Antigen: MS4A1
Clonality: Monoclonal
Clone: 93-1B3
Conjugation: CF640R
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Human
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